RNA viroids play a key role in cell regulation and human disease. An actinide depended RNA viroid biosphere has been described in metabolic syndrome x, neuronal degeneration, malignancy, psychiatric disorders, autoimmune diseases and acquired immunodeficiency syndrome. The RNA viroids arise from endosymbiotic actinidic archaea. The intracellular endosymbionts archaea and their intron derived viroids constitute the third element regulating the human body. A hypothesis regarding the role of endosymbiotic actinidic archaea and viroids in neuro-immuno-genomic-metabolic-endocrine regulation is put forward. The RNA viroids arising from endosymbiotic archaea contribute to the origin of new RNA viruses and retroviruses. The role of RNA viroids in human health and disease is crucial.
| The Full Book PDF |
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| Front Matter |
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| Chapter 1 RNA Viroids - Role in Metabolic/Endocrine Regulation – The Pathogenesis of Metabolic Syndrome with Coronary Artery Disease and Stroke |
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| Chapter 2 RNA Viroids in Genomic Regulation – The Pathogenesis of Trisomy 21 and Huntington’s Disease |
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| Chapter 3 RNA Viroids in Immune Regulation – Role in the Pathogenesis of Autoimmune Diseases – Multiple Sclerosis, Systemic Lupus Erythematosis and Rheumatoid Arthritis |
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| Chapter 4 RNA Viroids and Evolution of Viruses, Prokaryotes, Eukaryotes, Primates and Humans |
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| Chapter 5 RNA Viroids Mediated Model of Conscious/Quantal Perception and Regulation of Brain Function – Role in the Pathogenesis of Schizophrenia, Autism and Primary Seizure Disorder |
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| Chapter 6 RNA Viroids Regulate Cellular Organelle Function, Cell Growth, Cell Differentiation and Cell Death – Role in Neurodegenerations and Cancer |
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| Chapter 7 RNA Viroids, Prion Disease and Amyloidosis |
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| Chapter 8 RNA Viroidal Cloud in the Interstellar Space and Human Evolution |
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| Chapter 9 RNA Viroids and the Origin of Retroviral Resistance and Emerging Viral Pandemics – The Crossing of Species Barrier and New Viruses |
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| Back Matter |
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Dr. Ravikumar Kurup
Dr. Ravikumar Kurup trained in Internal Medicine, Neurology and Metabolic Medicine at Medical College, Trivandrum and Christian Medical College, Vellore. He holds a doctorate degree in Internal Medicine and Neurology. He is a member of the National Academy of Medical Sciences, India. He works as Professor of Metabolic Medicine and Metabolic Neurology at Metabolic Disorders Research Center, Trivandrum. He also works as Professor of Internal Medicine and Head of the divisions of Metabolic Medicine and Hematology at Medical College Hospital, Trivandrum. His areas of research interests are in Neurochemistry and Metabolic Medicine.
Parameswara Achutha Kurup
The Metabolic Disorders Research Centre, TC 4/1525, Gouri Sadan, Kattu Road North of Cliff House, Kowdiar PO Trivandrum, Kerala, India.
