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High Performance Thin Layer Chromatography and Its Role Pharmaceutical Industry: Review
Current Issue
Volume 5, 2018
Issue 3 (September)
Pages: 29-34   |   Vol. 5, No. 3, September 2018   |   Follow on         
Paper in PDF Downloads: 58   Since Oct. 10, 2018 Views: 1159   Since Oct. 10, 2018
Authors
[1]
Bandameedi Ramu, Department of Pharmaceutics, Kadiyala Vijaya Kumari College of Pharmacy, Hyderabad, India.
[2]
Kishore Babu Chittela, Department of Chemistry Koneru Lakshmaiah Education Foundation (KLEF) Deemed to be University, Vaddeswaram, Guntur, India.
Abstract
High Performance Thin Layer Chromatography (HPTLC) technique is a sophisticated and automated form of the thin-layer chromatography (TLC) with better and advanced separation efficiency and detection limits and is often an excellent alternative to GC and HPLC. Applications of HPTLC include phytochemical and biomedical analysis, herbal drug quantification, active ingredient quantification, fingerprinting of formulations, and check for adulterants in the formulations. HPTLC is useful in detecting chemicals of forensic concern. Various advance techniques in reference to HPTLC like hyphenations in HPTLC-MS, HPTLC-FTIR and HPTLC-Scanning Diode Laser have made HPTLC a power analytical tool in the field of analysis. Experts are of the opinion that HPTLC future to combinatorial approach and the utilization of instrumental HPTLC toward the analysis of drug formulations, bulk drugs, and natural products will increase in the future.
Keywords
High Performance Thin Layer Chromatography (HPTLC), Stability, Drugs, Herbal, Quality Control, Hyphenation
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