High Performance Thin Layer Chromatography and Its Role Pharmaceutical Industry: Review
[1]
Bandameedi Ramu, Department of Pharmaceutics, Kadiyala Vijaya Kumari College of Pharmacy, Hyderabad, India.
[2]
Kishore Babu Chittela, Department of Chemistry Koneru Lakshmaiah Education Foundation (KLEF) Deemed to be University, Vaddeswaram, Guntur, India.
High Performance Thin Layer Chromatography (HPTLC) technique is a sophisticated and automated form of the thin-layer chromatography (TLC) with better and advanced separation efficiency and detection limits and is often an excellent alternative to GC and HPLC. Applications of HPTLC include phytochemical and biomedical analysis, herbal drug quantification, active ingredient quantification, fingerprinting of formulations, and check for adulterants in the formulations. HPTLC is useful in detecting chemicals of forensic concern. Various advance techniques in reference to HPTLC like hyphenations in HPTLC-MS, HPTLC-FTIR and HPTLC-Scanning Diode Laser have made HPTLC a power analytical tool in the field of analysis. Experts are of the opinion that HPTLC future to combinatorial approach and the utilization of instrumental HPTLC toward the analysis of drug formulations, bulk drugs, and natural products will increase in the future.
High Performance Thin Layer Chromatography (HPTLC), Stability, Drugs, Herbal, Quality Control, Hyphenation
[1]
Sharma A., Shanker C., Tyagi L. K., Singh M., Rao V. Herbal Medicine for Market Potential in India: An Overview. Academic J. Plant Sci. 2008; 1 (2): 26-36.
[2]
Kadam P. V., Yadav K. N., Shivatare R. S., Pande A. S., Patel A. N., Patil M. J. Standardization of Gomutra Haritaki Vati: An Ayurvedic Formulation. Int. J. Pharm. Bio. Sci. 2012; 3 (3): 181–187.
[3]
Mukharjee P. K., Wahile A. Integrated approaches towards drug development from Ayurveda and other Indian system of medicines. J. Ethanopharmacol. 2006; 103 (1): 25-35.
[4]
Choudhary N., Sekhon B. S. An overview of advances in the standardization of herbal drugs. J. Pharm. Educ. Res. 2011; 2 (2): 55-70.
[5]
Amit J., Sunil C., Vimal K., Anupam P. Phytosomes: A revolution in herbal drugs. The Pharma Review 2007; 11-13.
[6]
Jena A., Saha D., Biswal B., Jana S. B., Koley A., Sur D., Battacharya A. Pharmacognostic Studies of leaves of Pterospermum Suberifolium. Int. J. Res. Pharmaceutical Biomed. Sci. 2011; 2 (1): 2229-3701.
[7]
Bagul M. S., Rajani M. Phytochemical evaluation of classical formulation: A case study. Indian Drugs 2005; 42: 15-19.
[8]
Jeganathan N. S., Kannan K. HPTLC Method for Estimation of Ellagic Acid and Gallic Acid in Triphalachurnam Formulations. Res. J. Phytochemistry 2008; 2 (1): 1-9.
[9]
Saraswathy A., Rukmani S., Ariyanathan S. Analysis of HinguvacadiCurna. Indian J. Trad. Knowledge 2009: 8 (3): 319-325.
[10]
Ahirwal B., Ahirwal D., Ram A. Evaluation of standards and quality control parameters of herbal drugs, Souvenir, recent trends in herbal therapy 2006: 25-29.
[11]
Wani M. S. Herbal medicine and its standardization. Pharma info. 2007; 5 (6): 1-6.
[12]
Ekka N. R., Namdeo K. P., Samal P. K. Standardization stratergies for herbal Drugs- an Overview. Res. J. Pharm. And Tech. 2008; 1 (4): 310-312.
[13]
Bele A. A., khale A. Standardisation of herbal drugs: an overview. Int. j. pharmacy 2011; 2 (12): 56-60.
[14]
US Pharmacopoeia National Formulary, USP 36/NF 31, United States Pharmacopoeial Convention. Inc., Rockville, MD, 2013.
[15]
Indian Pharmacopoeia, Volume-1, published by The Indian Pharmacopoeia Commission, Central Indian pharmacopoeia Laboratory Govt. Of India, Ministry of Health & Family Welfare Sector-23, Raj Nagar, Ghaziabad-201 00, 2007.
[16]
British Pharmacopeia (BP). Vol. II, Her Majesty‟s Stationary Office, London. 2001.
[17]
Patra K. C., Pareta S. K., Harwansh R. K., Kumar J. K. Traditional approaches towards standardization of herbal medicines -A review. J. Pharm. Sci. Technol. 2010; 2 (11): 372-379.
[18]
Folashade K. O., Omoregie E. H., Ochogu A. P. Standardization of herbal medicines - A review. Int. J. Biodiversity Conserv. 2012; 4 (3): 101-112.
[19]
Attimarad M., Mueen Ahmed K. K., Aldhubaib B. E., Harsha S. High-performance thin layer chromatography: A powerful analytical technique in pharmaceutical drug discovery. Symposium HPTLC 2011: 2 (2) 7: 1-75.
[20]
Reich E., Schibli A. Stationary Phases for Planar Separations - Plates for Modern TLC. LC GC 2005; 23: 58-69.
[21]
Shewiyo D. H., Kaaleb E., Rishab P. G., Dejaegherc B., Verbekec J. S., Heydenc Y. V. HPTLC methods to assay active ingredients in pharmaceutical formulations: A review of the method development and validation steps. J. Pharm. Biomedical Anal. 2012; 66: 11–23.
[22]
Shuijun L., Gangyi L., Jingying J., Xiaochuan L., Chen Y. Liquid chromatography – negative ion electrospray tandem mass spectrometry method for the quantification of ezetimibe in human. Plasma J. Pharm. Biomed. Anal. 2006: 40 (4): 987-992.
[23]
Patel R., Patel M., Dubey N., Dubey N., Patel B. HPTLC Method Development and Validation: Strategy to Minimize Methodological Failures. J. Food Drug Anal. 2012; 20 (4): 794-804.
[24]
Sherma J. Modern thin layer chromatography. J. AOAC Int. 2008; 91: 1142-1144.
[25]
Ravali R., Phaneendra M., BhanuJyothi K., RamyaSanthoshi L., Sushma K. Recent Trends in Analytical Techniques for the Development of Pharmaceutical Drugs. J. Bioanal. Biomed. 2011: 1-7.
[26]
Trinath M, Banerjee SK, Hari Hara Teja D, Bonde CG. Development and validation of spectrophotometric method for simultaneous estimation of sumatriptan and naproxen sodium in tablet dosage form. Pharm Sin. 2010; 1 (1): 36–41.
[27]
Ali NW, Abdelkawy M, Abdelhamid NS. Simultaneous determination of paracetamol and diphenhydramine hydrochloride mixture in the presence of their degradation products. IOSR J Pharm Biol Sci. 2013; 6 (5): 44–52.
[28]
Srivastava M. M. High-Performance Thin- Layer Chromatography (HPTLC). Springer Verlag Berlin Heidelberg 2011: 32-60.
[29]
Ge ZK, Luo YH, Zhao XY, Zhang YJ, Zhang H, Tian CC. Simultaneous determination of ibuprofen and diphenhydramine HCl in orally disintegrating tablets and its dissolution by reversed-phase high performance liquid chromatography (RP-HPLC). Afr J Pharm Pharmacol. 2011; 5 (18): 2100–2105.
[30]
Kalasz H., Bathori M. Pharmaceutical applications of TLC. LC–GC Eur 2001; 10: 311–321.
[31]
Sethi P. D. Quantitative Analysis of Pharmaceutical Formulations, High Performance Thin Layer Chromatography. CBS Publishers and Distributors, New Delhi, India, 1996: 1-30.
[32]
Gocan S. Stationary phases for thin-layer chromatography. J. Chromatogr. Sci. 2002; 40: 538–549.
[33]
Nyiredy S. Planar chromatographic method development using the PRISMA optimization system and flow charts. J. Chromatogr. Sci. 2002; 40: 553–563.
[34]
Koll K., Reich E., Blatter A., Veit M. Validation of standardized high-performance thin-layer chromatographic methods for quality control and stability testing of herbals. J. AOAC Int. 2003; 86: 909-915.
[35]
Sherma J. Review of HPTLC in drug analysis: 1996-2009. J. AOAC Int. 2010; 93: 754-764.
[36]
Kowalska, T.; Sajewicz, M.; Sherma, J. Eds. Planar Chromatography-Mass Spectrometry CRC Press/Taylor & Francis Group: Boca Raton, FL, 2016.
[37]
Jinu John., Ankit Reghuwanshi., Usha K. Aravind., Aravinda kumar, C. T. Development and validation of a HPTLC method for thedetermination of cholesterol concentration. Journal of food and drug analysis. 2015, 2 3. 219-224.
