Antibiotic Susceptibility Patterns of Vibrio cholera O1 Isolated During Cholera Outbreak in Uzebba (Edo State)
[1]
Ukaji D. C., Department of Medical Laboratory Science, Madonna University, Elele Campus, Rivers State, Nigeria.
[2]
Kemajou T. S., Department of Medical Laboratory Science, Madonna University, Elele Campus, Rivers State, Nigeria.
[3]
Ajugwo A. O., Department of Medical Laboratory Science, Madonna University, Elele Campus, Rivers State, Nigeria.
[4]
Ezeiruaku F. C., Department of Medical Laboratory Science, Niger Delta University, Bayelsa State, Nigeria.
[5]
Eze E. M., Department of Medical Laboratory Science, Rivers State University of Science and Technology, Nkpolu, Port-Harcourt, Rivers State, Nigeria.
A survey was carried out to determine the presence and antibiotic susceptibility of vibrio cholerae O1 from stool samples during cholera outbreak in Uzebba, Edo – State.Strains of Vibrio cholerae O1 isolated from patient stool samples using Thiosulphate Citrate Bile Salt Sucrose (TCBS) agar during cholera were identified using standard biochemical tests and serotypes using polyvalent sera. Disc diffusion method of Kirby-Bauer was used to test the susceptibility of Vibrio cholerae O1 to ten antimicrobial agents.All isolates were (100%) susceptible to ciprofloxacin, pefloxacin and sparfloxacin. Some strains showed moderate sensitivity to gentamicin, streptomycin and augumentin. Vibrio cholerae O1 recorded the least susceptibility pattern of 15.8% to tetracycline (19%). From our findings, quinolones (Ciprofloxacin, Pefloxacin and Sparfloxacin) are still useful for the treatment of cholera, while the least sensitivity to tetracycline still generate questions and concern, especially in regions where patients can not afford the cost of quinolones.
Vibrio cholerae, Cholera Outbreak, Antibiotic Susceptibility,Uzebba (Edo – State)
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