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Hematological Changes in Patients Infected by Plasmodium Falciparum Versus Patients Infected by Plasmodium Vivax
Current Issue
Volume 4, 2019
Issue 4 (August)
Pages: 48-51   |   Vol. 4, No. 4, August 2019   |   Follow on         
Paper in PDF Downloads: 8   Since Nov. 21, 2019 Views: 76   Since Nov. 21, 2019
Authors
[1]
Abdelnassir Mohammed Ahamed, Department of Pathology, Faculty of Medicine and Health Sciences, University of West Kordufan, Elnihoud, Sudan.
[2]
Hafiz Ahmed Hobiel, Department of Biochemistry, Faculty of Medicine and Health Sciences, University of West Kordufan, Elnihoud, Sudan.
[3]
Mohammed Saeed Elsammani, Department of Basic Medical Sciences, Faculty of Applied Medical Sciences, University of Albaha, Albaha, Saudi Arabia.
Abstract
Malaria is a major public health problem in tropical and subtropical countries. P. falciparum and P. vivax are the two major species of malaria infecting humans. Although emphasis on P. falciparum is appropriate, the burden of vivax malaria should be given due attention as almost 40% of the world population are at risk of vivax malaria. This study was aimed to assess the hematological changes in patients with P. falciparum and patients with P. viva malaria. A total of 264 participants (173 P. falciparum and 91 P. vivax) were enrolled in this study, all of them were randomly selected from Elnihoud Teaching Hospital, Elnihoud Locality, West Kordufan State, Sudan. Questionnaire was filled for every participant and thick and thin blood films for malaria were prepared and stained by giemsa stain and the CBC was done by sysmex automated hematological analyzer. The mean Hb level for P. vivax infected patients was significantly lower than that for P. falciparum infected patients (p-value = 0.037). Low TWBCs count was significantly higher among P. vivax infected patients compared to those with P. falciparum infection (p-value = 0.018). Low MCH was significantly higher among P. vivax infected patients compared to those with P. falciparum infection (p-value = 0.019). Hb was positively and significantly correlated with MCV and MCH (p-value < 0.0001 for both). Both P. falciparum and P. vivax can cause hematological changes. Leucopenia was significantly predominant among P. falciparum infected patients and hypochromic anemia was significant predominant among P. vivax infected patients.
Keywords
Falciparum Malaria, Thrombocytopenia, Leucopenia, Hypochromic Anemia
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