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Effects of Caffeine Consumption on Blood Pressure Among Adults at Risk for Increased Intra-ocular Pressure
Current Issue
Volume 2, 2017
Issue 6 (November)
Pages: 25-30   |   Vol. 2, No. 6, November 2017   |   Follow on         
Paper in PDF Downloads: 22   Since Jan. 8, 2018 Views: 580   Since Jan. 8, 2018
Oyakhire Musa Oseni, Department of Physiology, Faculty of Basic Medical Sciences, College of Medicine, Ambrose Alli University, Ekpoma, Nigeria.
Ernest-Nwoke Israel Onyebuchi, Department of Physiology, Faculty of Basic Medical Sciences, College of Medicine, Ambrose Alli University, Ekpoma, Nigeria.
Ovienria Abhuluime Wilson, Department of Ophthalmology, Irrua Specialist Teaching Hospital, Irrua, Nigeria.
Akpamu Uwaifoh, Department of Physiology, Faculty of Basic Medical Sciences, College of Medicine, Ambrose Alli University, Ekpoma, Nigeria.
This study examines the effects of caffeine consumption on blood pressure among adults at risk for increased intraocular pressure attending the Ophthalmic Clinic of a Specialist Teaching Hospital in Nigeria. The study is a retrospective study conducted using questionnaire to obtain information on consumption of caffeinated drinks, coffee, tea and chocolate via the National Health Service semi-quantitative food frequency questionnaire assessment. Subjects who met the criteria and gave informed consent were recruited for blood pressure measurement and the result recorded. Statistical analysis was then carried out and simple descriptive analysis done. The results showed that 388 subjects completed the study with 201 subjects having positive history of caffeine intake. This amounted to a 51.80% prevalence of caffeine consumption among adults attending the Ophthalmic Clinic. Participants positive to caffeine consumption (132.31±16.44/82.41±9.14mmHg) presented significantly higher (p<0.05) mean blood pressure than participants negative to caffeine intake (121.11±9.18/77.75±10.32mmHg). Also, age and gender were observed to significantly influence (p<0.05) systolic blood pressure in participants positive for caffeine consumption as compared to those negative for caffeine intake. The results suggest that caffeine consumption, female gender and advancing age are risk factors for the development of hypertension in adult population at risk of increased intraocular pressure and vice vasa.
Caffeine, Blood Pressure, Increased Intraocular Pressure, Ophthalmic Clinic
Nawrot P, Jordan S, EastNawrot P, Jordan S, Eastwood J, Rotstein J, Hugenholtz A, Feeley M. Effects of caffeine on human health. Food Addit. Contam. 2003; 20, pp. 1-30.
Klein BEK, Klein R, Knudtson MD. Intra-ocular pressure and systemic blood pressure: a longitudinal perspective: the Beaver Dam eye study. British Journal of Ophthalmology2005; 89:284-287.
Andersen LF, Jacobs DR Jr, Carlsen MH, Blomhoff R. Consumption of coffee is associated with reduced risk of death attributed to inflammatory and cardiovascular diseases in the Iowa Women’s Health Study. Am J Clin Nutr.2006;83:1039-46.
James JE. Critical review of dietary caffeine and blood pressure: A relationship that should be taken more seriously. Psychosom Med. 2004;66:63-71.
American Heart Association (AHA). Statement on Caffeine. 2007; Available from: URL: http://www.americanheart. org/presenter. jhtml.
Winkelmayer WC, Stampfer MJ, Willett WC, Curhan GC. Habitual caffeine intake and the risk of hypertension in women. JAMA. 2005;294:2330-5.
Lopez-Garcia E, van Dam RM, Willett WC. Coffee consumption and coronary heart disease in men and women: a prospective cohort study. Circulation2006; 113(17):2045–2053.
Whitsett TL, Manion CV, Christensen HD. Cardiovascular effects of coffee and caffeine. American Journal of Cardiology1984; 53:918-922.
Smits P, Thien TH, Van′tlaar A. The cardiovascular effects of regular and decaffeinated coffee. British Journal of Pharmacology1985; 19:852.
Mathew RJ, Wilson WH. Caffeine-induced changes in cerebral circulation. Stroke1985; 16:814-817.
Bottcher M, Czernin J, Sun KT. Effect of caffeine on myocardial blood flow at rest and during pharmacological vasodilation. Journal of Nucleic Medicine1995; 36:2016-2021.
Lofti K, Grunwald JE. The effect of caffeine on the human macular circulation. Investigative Ophthalmology and Visual Science1991;32:3028-3032.
Araoye MO. Ch 7, ‘Sampling techniques’, In: Research methodology with statistics, 2008, Ilorin, Nigeria: University Press, 2008; Pp 68-91.
Willett WC, Sampson L, Stampfer MJ, Rosner B, Bain C, Witschi J, et al. Reproducibility and validity of a semiquantitative food frequency questionnaire. Am. J. Epidemiol.1985; 122:51-65.
WMA. World Medical Association Declaration of Helsinki ethical principles for medical research involving human subjects. 2000.
Cromie W. Coffee gets cleared of blood pressure risk. Harvard Gazette2005;10:2006.
Serafin WE. Goodman and Gillman’s Pharmacological Basis of Therapeutics. In: Hardman JG, Limbird LE, Molinoff PB, Ruddon RW, Goodman Gillman A, editors. 9th edition. New York: McGraw Hill. 1996; 673-679.
Sung BH, Lovallo WR, Whitsett T, Wilson MF. Caffeine elevates blood pressure response to exercise in mild hypertensive men. American Journal of Cardiology1995;8:1184-1188.
Sung BH, Lovallo WR, Pincomb GA, Passey RB, Wilson MF. Effects of caffeine on blood pressure response during exercise in normotensive young men. American Journal of Cardiology1990;65:909-913.
Pincomb GA, Lovallo WR, McKey BS, Sung BH, Passey RB, Everson SA, Wilson MS. Acute blood pressure elevations with caffeine in men with borderline systemic hypertension. American Journal of Cardiology1996;77:270-274.
Pincomb G, Sung B, Sausen K, Lovallo W, Wilson M. Consistency of cardiovascular response pattern to caffeine across multiple studies using impedance and nuclear cardiography. Biology and Psychology1993; 6:131-138.
Pincomb GA, Wilson MF, Sung BH, Passey RB, Lovallo WR. Effects of caffeine on pressor regulation during rest and exercise in men at risk for hypertension. American Journal of Cardiology1991;122:1107-1115.
Pincomb GA, Lovallo WR, Passey RB, Wilson MF. Effect of behavior state on caffeine’s ability to alter blood pressure. American Journal of Cardiology1988;61:798-802.
Pincomb GA, Lovallo WR, Passey RB, Whitsett TL, Silverstein SM, Wilson MF. Effects of caffeine on vascular resistance, cardiac output and myocardial contractility in young men. American Journal of Cardiology1985;56:119-122.
Lovallo WR, Pincomb GA, Sung BH, Everson SA, Passey RB, Wilson MF. Hypertension risk and caffeine’s effect on cardiovascular activity during mental stress in young men. Health Psychology1991;10:236-243.
Lane JD, Williams RB. Cardiovascular effects of caffeine and stress in regular coffee drinkers. Psychophysiology1987;24:157-164.
Rakic V, Burke V, Beilin LJ. Effects of coffee on ambulatory blood pressure in older men and women: a randomized controlled trial. Hypertension1999; 33:869-873.
Jee SH, He J, Whelton PK, Suh I, Klag MJ. The effect of chronic coffee drinking on blood pressure: a meta-analysis of controlled clinical trials. Hypertension 1999;33:647-52.
Noordzij M, Uiterwaal CS, Arends LR, Kok FJ, Grobbee DE, Geleijnse JM. Blood pressure response to chronic intake of coffee and caffeine: a meta-analysis of randomized controlled trials. J Hypertens 2005;23:921-8.
Le A, Mukesh BN, McCarty CA, Taylor HR. Risk factors which are associated with the incidence of open – angle glaucoma: the visual impairment project. Investigative Ophthalmology and Visuall Science2003; 44 (9): 3783-3789.
Lee JS, Kim SM, Choi HY, Oum BS. A relationship between the intraocular pressure, age and the body mass index in a Korean population. Journal of Korean Ophthalmology Society2003; 44 (7): 1559-1566.
Hennis A, Wu SY, Nemesure B, Leske MC. Hypertension, diabetes and longitudinal changes in the intra-ocular pressure. Ophthalmology2003; 110(5): 908-914.
Leske MC, Connell AMS, Wu SY, Nemesure B, Li X, Schachar A. Incidence of open–angle glaucoma. Archives of Ophthalmology2001; 119:89-95.
Bonomi L, Marchini G, Marraffa M, Bernardi P, Morbio R, Varotto A. Vascular risk factors for primary open angle glaucoma. Ophthalmology2000; 107 (7): 1287-1293.
Dielemans I, Vingerling JR, Algra D, Hofman A, Grobbee DE. Primary open -angle glaucoma, the intraocular pressure and the systemic blood pressure in the general elderly population. Ophthalmology1995; 102 (1): 54-60.
Klein BB, Klein R. The intra-ocular pressure and the cardiovascular risk variables. Archives of Ophthalmology1981; 99: 837-839.
Foster PJ, Machin D, Wong TY, Ng TP, Kirwan JF, Johnson GJ. Determinants of the intraocular pressure and its association with glaucomatous optic neuropathy in Chinese Singaporeans: the Tanjong Pagar study. Investigative Ophthalmology and Visual Science2003; 44:3885-3891.
Rochtchina E, Mitchell P, Wang JJ. Relationship between age and intra-ocular pressure: the Blue Mountains eye study. Clinical Experimental Ophthalmology2002;30(3):173-175.
Nomura H, Shimokata H, Ando F, Miyake Y, Kuzuya F. Age related changes in the intra-ocular pressure in a large Japanese population. Ophthalmology1999; 106(10):22-33.
McLeod SD, West SK, Quigley HA, Fozard JL. A longitudinal study of the relationship between the intraocular and the blood pressures. Investigative Ophthalmology and Visual Science1990; 31: 2361-2366.
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