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Plasma Proteins in Enterica Serovar Typhi Patients in Merowe Locality Northern Sudan
Current Issue
Volume 1, 2016
Issue 1 (July)
Pages: 10-13   |   Vol. 1, No. 1, July 2016   |   Follow on         
Paper in PDF Downloads: 30   Since Jun. 25, 2016 Views: 1454   Since Jun. 25, 2016
Authors
[1]
Nagah A. A. Mohamed, Department of Biochemistry Faculty of Medicine, Ondokuz Mayis University, Samsun, Turkey.
[2]
Mohammed Amanullah, Department of Clinical Biochemistry, College of Medicine, King Khalid University, Abha, Saudi Arabia.
[3]
Mohieldin Omer, Faculty of Medical Laboratory Sciences, Sudan University of Science and Technology, Khartoum, Sudan.
Abstract
The study entailed a quantitative assessment of serum total protein, albumin, globulin, and albumin: globulin ratio in individuals who diagnosed positively with typhoid fever and detection any alteration in plasma protein in receptiveness to typhoid titers. One hundred positively diagnosed with typhoid infection mean age (41.5 ± 2.1) years on zero day treatments. In addition to healthy one hundred individuals mean age (42.9 ± 1.9) years were recruited in this study. There were significant difference P. value = 0.000 in total protein, serum albumin, serum globulin and A/G ratio for typhoid positive and negative, mean (8.4±0.01,6.8±0.06), (3.5±0.01, 4.1±0.03), (4.9±0.01, 2.8±0.06), (0.7 ± 0.003, 1.5 ± 0.02) respectively No significant difference, P. value was 0.632, 0.832 and 0.760 serum total protein (7.5 ± 0.92, 7.6 ± 0.79) serum albumin (3.8 ± 0.38, 3.8 ± 0.37) and serum globulin (3.8 ± 0.16, 3.9 ± 0.16) for males and females respectively. Also no significant difference, P. value was 0.11, 0.60, and 0.06 serum total protein (8.4 ± 0.01, 8.4± 0.02) serum albumin (3.5 ± 0.01, 3.5 ± 0.01) and serum globulin (5.0 ± 0.01, 4.9 ± 0.01) for titer 1/160 and titer 1/320. Low albumin level and hypoglycemia should be surveillant when anti typhoid pharmaceutical commenced.
Keywords
Typhoid, Salmonella Titre, Serum Total Proteins, Albumin, Globulin
Reference
[1]
World health organization (2000). WHO position paper. Wkly Epidomol Rec. 75; 25–64.
[2]
Falkenhorst G, Ceper T. H, Strid M. A, Mølbak K, Krogfelt K. A. (2013). Serological follow-up after non-typhoid salmonella infection in humans using a mixed lipopolysaccharide ELISA. Int J Med Microbiol. 303(8): 533-8.
[3]
Năşcuţiu AM. (2014). Role of Salmonella serology a Century after the Widal era. Roum Arch Microbiol Immunol. 73(3-4): 105-17.
[4]
Jagadish K, Patwari A. K., Sarin S. K., Prakash C., Srivastava D. K., Anand V. K. (1994). Hepatic manifestations in typhoid fever. Indian Pediatr. 31(7): 807-11.
[5]
Igbal, S. M. J., Serfraz, M. M. and Khan, M. N. (2004). Clinical spectrum of Typhoid fever in children. Pakistan journal of medical of Health Sciences. 10 (4): 366-367.
[6]
Ozen, H. G.; Sec meer, G.; Kanra, Z.; Ecevit, M.; Ceyhan, A. and Dursun, Y. A., (1995). Typhoid fever with very high transaminase Levels. Turky, Pediatre, 37 (2), 169-171.
[7]
Amen Shamim, Ayesha, Bilal Hussain. (2012). Study of Biochemical Changes and Elevated Levels of Enzymes in Salmonella typhi Infected Patients in Pakistani Population. Int. J. Bio Automation. 16(1): 33-42.
[8]
Emenuga V. N., Ureme S. O., Ohanu M. E., Ejezie F. E. and Nnabuchi C. I. (2014). Some Hematological and Biochemical Profiles of Typhoid Fever in IGBOS of Nigeria. Indian journal of applied research. 3(4): 330-332.
[9]
Janice, T. Busher, (1990). Clinical Methods; The history, physical and laboratory examination. 3rd edition chapter 101. Boston; Butler Worths; Gerogia.
[10]
Crump J. A, Luby S. P. and Mintz E. D. (2004). The Global burden of typhoid Fever. Bull world Health organ. 38: 346-353.
[11]
Crump J. A, Heyderman R. S. (2015). A Perspective on Invasive Salmonella Disease in Africa. Clin Infect Dis. 1; 61 Suppl 4:S235-40.
[12]
Bernardi M, Ricci CS, Zaccherini G. (2014). Role of human albumin in the management of complications of liver cirrhosis. J Clin Exp Hepatol. 4(4):302-11.
[13]
Reinoso, M. A. C.; Whitly, J. J. and Schwarzenberg, S. J. (1998). Lysinuric Protein Intolerance Masquerading as Celiac Disease; Acase Report. J Pediatr. 132(1): 153-155.
[14]
Abro A. H., Abdou, J. L., Gangwani A. M., Ustadi N, J., Younis, H. S., Hussaini S. (2009). Hematological and Biochemical change in typhoid fever. Pak J Med Sci. 25(2): 166-171.
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