Influence of Olive Leaf Extract and Stem Cell Therapy on Hepatic Cellular Injury Induced by Gamma Radiation in Albino Rats: Histological, Histochemical and Immunohistochemical Study
Radiation, Liver, Olive, Stem Cells, Regenerative Medicine and Histochemsitry
[1]
Tolman, KG., Fonseca, V., Tan, MH., and Dalpiaz, A. (2004): Narrativereview: hepatobiliary disease in type 2 diabetes mellitus. Ann Intern Med., 141: 946-956.
[2]
Steel, GG. (1996): From targets to genes: a brief history of radio sensitivity. Phys Med Biol., 41: 205-222.
[3]
Hall, EJ. (2000): A radiation biologist looks to the future. Int J RadiatOncolBiol Phys., 46: 1-2.
[4]
Samarth, RM., and Kumar, A. (2003): MenthaPiperia leaf extract provides protection against radiation induced chromosomal damage in bone marrow of mice. Indian J Exp Biol., 41: 229-237.
[5]
Bhosle, SM., Huilgol, NG., Mishra, KP. (2005): Enhancement of radiation induced oxidative stress and cytotoxicity in tumor cells by ellagic acid. ClinChimActa., 359: 89-100.
[6]
Vincent, EG. (2008): Protection against radiation-the second line of defense. http://www.vincegiuliano.name/PROTECTION%20AGAINST%20RADIATIONc.htm#_ftn1
[7]
Gerber, M., Boutron-Ruault, MC., Hercberg, S., Riboli, E., and Scalbert, A. (2002): Food and cancer: state of the art about the protective effect of fruits and vegetables. Bull Cancer., 89: 293-312.
[8]
El-Habit, OH. Saada, HN., Azab, KS., Abdel-Rahman, M., and El-Malah, DF. (2000): The modifying effect of B-carotene on gamma radiation-induced elevation reactions and genotoxicity in male rat. Mutat Res., 466: 179-186.
[9]
Omar, SH. (2010): Oleuropein in Olive and its pharmacological effects. Sci.Pharm., 78:133-154.
[10]
Visioli, F., Poli, A., Galli, C. (2002): Antioxidant and other biological activities of phenols from olives and olive oil. Med. Res. Rev., 22: 65–75.
[11]
Andreadou, I.., Iliodromitis, EK., Mikros, E., Constantinou, M., Agalias, A., Magiatis, P., Skaltsounis, AL., Kamber, E., Tsantili-Kakoulidou, A., and Kremastinos, DT. (2006): The olive constituent oleuropein exhibits anti-ischemic, antioxidative, and hypolipidemic effects in anesthetized rabbits. JNutr., 136: 2213–2219.
[12]
Visioli, F., and Galli, C. (2001): Antiatherogenic components of olive oil. Curr. Atheroscler. Rep., 3: 64–67.
[13]
Carluccio, MA., Siculella, L., Ancora, MA., Massaro, M., Scoditti, E., Storelli, C., Visioli, F., Distante, A., and DeCaterina, R. (2003): Olive oil and red wine antioxidant polyphenols inhibit endothelial activation: antiatherogenicproperties of Mediterranean diet phytochemicals. Arterioscler. Thromb. Vasc. Biol., 23(4):622-629.
[14]
Hamdi, HK., and Castellon, R. (2005): Oleuropein, a non-toxic olive iridoid, is an anti-tumor agent and cytoskeleton disruptor. Biochem. Biophys. Res. Commun., 334: 769–778.
[15]
Menendez, JA., Vazquez-Martin, A., Colomer, R., Brunet, J., Carrasco-Pancorbo, A., Garcia-Villalba, R., Fernandez-Gutierrez, A., and Segura-Carretero, A. (2007): Olive oil's bitter principle reverses acquired autoresistance to trastuzumab (Herceptin™) in HER2-overexpressing breast cancer cells. B.M.C. Cancer., 7: 80-87.
[16]
Furneri, PM., Marino, A., Saija, A., Ucella, N., and Bisignano, G.(2002): In vitro antimycoplasmal activity of oleuropein. Int. J. Antimicrob. Agents., 20: 293–296.
[17]
Caturla, N., Perez Fons, L., Estepa, A., and Micol, V. (2005): Differential effects of oleuropein, a biophenol from Oleaeuropaea, on anionic and zwiter ionic phospholipid model membranes. Chem. Phys. Lipids., 137: 2–17.
[18]
Fredrickson, WR. (2000): Method and composition for antiviral therapy with olive leaves. Global Veterinaria., 6:117-844.
[19]
Ma, SC., He, ZD., Deng, XL., But, PP., Ooi, VE., Xu, HX., Lee, SH., and Lee, SF. (2001):In vitro evaluation of secoiridoidglucosides from the fruits of Ligustrumlucidumas antiviral agents. Chem. Pharm. Bull., 49: 1471–1473.
[20]
Seo, GS. (2011): Stem cell properties of therapeutic potential. Korean J Gastroenterol., 58: 125-132. 19.
[21]
Shrihari, TG. (2011): Cancer Stem Cells - Therapeutic Boon! J Cancer SciTher., 3: 197-200. 20. Quante M.
[22]
Wang, TC. (2009): Stem cells in gastroenterology and hepatology. Nat Rev GastroenterolHepatol., 6: 724-737.
[23]
Navarro-Alvarez, N., Soto-Gutierrez, A., Kobayashi, N. (2009): Stem cell research and therapy for liver disease. Curr Stem Cell Res Ther., 4: 141-146.
[24]
Wainstein, J., Ganz, T., Boaz, M., Dayan, YB., Dolev, E., Kerem, Z., and Madar, Z. (2012): Olive leaf extract as a hypoglycemic agent in both human diabetic subjects and in rats. Journal of Medicinal Food: 15: 605–610.
[25]
Bancroft, D., and Gamble, M. (2008): Bancroft's Theory and Practice of Histological Techniques. 6th Ed. Elsevier, Churchill Livingst one, Edinburgh, Scotland., Pp 178-186, 221-224.
[26]
Hammer, Ø., Harper, DAT., Ryan, PD. (2001): PAST: Paleontological Statistics Software Package for Education and Data Analysis. Palaeontologia Electronica., 4(1): 9-15.
[27]
Jagetia, GC. (2007): Radioprotective potential of plants and herbs against the effects of ionizing radiation. J. Clin. Biochem. Nutr., 40:74-81.
[28]
Kunwar, A., Bansal, P., Kumar, SJ., Bag, PP., Paul, P., Reddy, ND., Kumbhare, LB., Jain, VK., Chaubey, RC., Unnikrishnan, MK., and Priyadarsini, KI. (2010): In vivo radioprotection studies of 3,3'-diselenodipropionic acid, a selenocystine derivative. Free Rad. Biolo. Medic., 48: 399–410.
[29]
Saada, HN., Ussama, ZS., Mahdy, AM. (2003): Effectiveness of Aloe vera on the antioxidant status of different tissue in irradiated rats.J. Pharmazie., 58:1.
[30]
Azab, KhSh. (2007): Modulation of radiation injuries in rats receiving multiple doses of Aloe Vera. Egypt. J. Rad. Sci. and Applic., 20:17-28.
[31]
Ammar, AA. (2009): Evaluation of the protective role of wheat germ oil in irradiated rats. Isotope Rad. Res., 41: 911-920.
[32]
El-Masry, FS and Saad, TM. (2005): Role of selenium and vitamin E in modification of radiation disorders in male albino rats: Isotope Rad. Res.37., 5: 1261-1273.
[33]
Agarwal, A., and Kale, RK. (2001): Radiation induced oxidative damage: mechanisms and significance. Ind. J. Exp. Boil., 39: 291–309.
[34]
Mrcillo, MA., Rucandio, MI., Santamaria, J. (2000): Effect of gamma irradiation and lipid peroxidation in rats. Cell Mol. Biol., 92: 337.
[35]
Dawson, LA., Normalle, D., Balter, JM., McGinn, CJ., Lawrence, TS., and Haken Ten, RK. (2002): Analysis of radiation induced liver disease using the Lyman NTCP model. Int. J. Rad. Oncol. Biol. Phys., 53: 810–821.
[36]
Koc, M., Taysi, S., Buyukokuroglu, ME., and Bakan, N. (2003): Melatonin protects rat liver against irradiation induced oxidative injury. J. Rad. Res., 44: 211–215.
[37]
Song, LH., Yan, HL., and Cai, DL. (2006): Protective effects of soy bean is of lavone against gamma irradiation induced damages in mice. J. Rad. Res. Tokyo., 47(2): 157–165.
[38]
Rezkm, RG. (2005): Modulatory role of AloeVera on gamma irradiation induced histological changes in different tissues of rats. Egypt. J. Rad. Sci., Applic., 18(1): 97-115.
[39]
Said, UZ., Rezk, RG., a, HN. (2005): Role of calcium pantothenate in recovery of radiation induced injury to mammalian organs. Egypt.J.Rad.Sci., Applic., 18(1):17-38.
[40]
Soliman, O., Abd El Maguid, A., Hafez, MN. (2007): Histological and histochemical studies on liver of rat subjected to synergistic effect of natural and synthetic food colorants and/or gamma irradiation. Egypt.J.Rad.Sci.Applic., 20(1): 195-214.
[41]
Kafafy, YA., Abu Gabal, HA., Roushdy, HM., Abu Sinna, GM., andAshry, OM. (2001): Bone marrow transplantation controlling hormonal and structural changes in radiation exposed pregnant mice and their developing embryos. Egypt. J. Rad. Sci. Applic., 14(1): 1–23.
[42]
Kropacova, K., Slovinska, L., Misurova, E. (2002): Cytogenetic changes in the liver of progeny of irradiated male rats. J. Rad. Res., 43: 125–133.
[43]
Rady, MI., Abu Nour, SM., Khalil, HM. (2008): Effect of gamma radiation on albino rat's liver and the possible protective role of β-carotene on the histological and ultra structural changes. Egypt. J. Rad. Sci., Applic., 21(2): 373-388.
[44]
Jirtle, RL., Anscher, MS., Alati, T. (1990): Radiation sensitivity of the liver. In: ''Advances in Radiation Biology''. Academic Press, San Diego. 14.
[45]
Majno, G., and Joris, I. (1996): Cells, tissues and diseases. In: "Principal of general patholgy". Part I, Cellular Patho. Blackwell Sci. 202- Yarmonenko, SP. (1998): In radiobiology of human and animals. Mir. Publisher, Moscow., 33.
[46]
Zavodnik, LB., Kravchuk, R., Artsukevich, A., Chumachenko, S., Sheibak, M., Ovchinnikov, V., and Buko, V. (2003): Dynamicsofstructural changes in rat liver after single dose of gamma irradiation. Rad. Biol. Radioecol., 43(6): 618.
[47]
Guryey, DV. (2005): Histologic assessment of regenerating rat liver under low-dose rate radiation exposure. Inter. Congress Series., 1276: 181.
[48]
Hagen, V. (1989): Biochemical aspects of radiation biology. Experientia., 45:7.
[49]
Geraci, JP., and Mariano, MS. (1993):Radiation hepatology of the rat: Parenchymal and nonparenchymal cell injury. Rad. Res., 129: 322.
[50]
Levier, DG., Brown, RD., Mccay, TA., and Fuchs, BA.(1993): Hepatic and splenic phagocytosis in female mice implanted with morphine sulfate pellets. J. Pharmacol. Exp. Ther., 267(1):357-63.
[51]
Trigueiro, MS., General, F., Chossegros, S. (1992): Lack of hepatocyte involvement in the genesis of the sinusoidal dilatation related to heroin addiction a morphometric study. Virchows. Arch. Pathol. Anat. Histopathol., 420(2):149-153.
[52]
Curran, RC. (2000): Colour atlas of histology. Harvery miller publishers, Oxford University. Press. 4th ed.
[53]
Ahlersova, E., Ahlers, I., Slavkovska, M. (1981): Metabolic changes after non-lethal X-irradiation of rats. Folia. Biol., 27: 404.
[54]
El-Gharib, RF., Fahmy, N., Abd El Maguid, A., and Saber, FH. (1999): Studies on radiation injury and recovery on liver using silymarin. Egypt. J. Histol., 22(1-2):111.
[55]
AbdElMaguid, A., ElGharib, R., Ahmed, KA. (2004): Possible protectiveroleofmelatoninagainstradiationinducedhistopathologicaland histochemical changes in the liver of male albino rats. Egypt. J. Ger.Soc. Zool., 45C:1.
[56]
Radosevich, PM., Williams, PE., Brooks, LD., McRae, JR., Steiner, KE., and Cherrington, AD. (1984): Effect of morphine on glucose homeostasis in the conscious dog. J. Clin. Invest., 74:1473-1480.
[57]
Khamis, FI., Abu-Gabal,H.,Roushdy, HM. (1989): Control of radiation induced changes in certain serum and liver enzymes through bone marrow transplantation. 1st Internat. Conf. Low Cost Exp. Biophys. Cairo Univ.
[58]
Serizawa, N., Takei, Y., Okubo, H., Yamasina, S.,Enomoto, N., and Sato, N. (2006): Effect of low molecular weight heparin on the commitment of bone marrow cells to liver sinusoidal endothelial cells in CC14-induced liver injury. Hepatol. Res., 34(4): 207–213.