Antibacterial Potential of Leave Extract of Different Species of Ocimum (O. Gratisimum & O. Guineas) on Bacterial Isolates from Urinary Tract
[1]
Orhue P. O., Department of Microbiology, Faculty of Natural Sciences; Ambrose Alli University, Ekpoma, Nigeria.
[2]
Momoh A. R. M., Department of Medical Microbiology, Faculty of Clinical Sciences, College of Medicine; Ambrose Alli University, Ekpoma, Nigeria.
[3]
Igumbor E. O., Department of Microbiology, Faculty of Natural Sciences; Ambrose Alli University, Ekpoma, Nigeria.
[4]
Esumeh F. I., Department of Microbiology, Faculty of Natural Sciences; Ambrose Alli University, Ekpoma, Nigeria.
Urinary tract infection is a threat to the world population and economic, and the situation is further worsen by the high costs and hazardous side-effects of synthetic drugs in mix of drug resistance. The importance of this study lies in evaluating the antimicrobial potentials of different solvents extracts of Ocimum spp against some human bacteria causing urinary tract infections. Following standard laboratory procedures, the leaves extracts of Ocimum gratisimum and Ocimum guineas were studied on Gram positive bacteria (Staphylococcus aureus) and two strains of Gram-negative bacteria (Escherichia coli and Pseudomonas aeruginosa). The results showed that the petroleum ether and 1%HCl extracts showed high antibiotic potentials that are similar to standard antimicrobial drugs. Worrisome is the observed insensitivity against the urinary tract infection herein studied with the water and ethanolic extracts of Ocimum gratisimum and Ocimum guineas. However, acetone extract in Ocimum guineas was sensitive to S. aureus only. Conclusively, petroleum ether and 1%HCl extracts may served as preferred extraction solvents for Ocimum gratisimum and Ocimum guineas leave considering the inhibitory activities against urinary tract microbes.
Herbs, Therapeutic Potential, Antimicrobial, Urinary Tract Infection, Ocimum Species
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