[1]
Tolulope Iorwuese Ade, Department of Microbiology, Faculty of Pure and Applied Sciences, Federal University, Wukari, Nigeria.
[2]
Ebuara Francis Ushie, Department of Microbiology, Faculty of Pure and Applied Sciences, Federal University, Wukari, Nigeria.
The emergence of antibiotic resistant bacteria has over the years risen to become a major and significant issue in public and community health. Urinary tract infection is one of the major causes of morbidity in humans especially in developing countries. The etiology of UTI and antibiotic sensitivity pattern varies with the widespread availability of antimicrobial agents. The research study was conducted to assess the sensitivity and resistance patterns of uropathogenic Escherichia coli and Klebsiella spp isolated from urine samples of patients suffering urinary tract infection in Wukari, Taraba State. Of the one hundred and twelve (112) patient-respondents, females represented the major part with 56.25% while the male gender was in the minority with 43.75%. From the collected urine specimen, E. coli and Klebsiella spp were recovered seventy-three (73) and fifty-four (54) times respectively and were tested against different concentrations of antibiotics. Of the tested antibiotics, the uropathogens were more sensitive to Tarivid, Nalidixic acid, Gentamicin, Augmentin, Ciprofloxacin, Streptomycin and Reflacine. While E. coli was resistant to Septrin, Klebsiella was sensitive. Both bacteria isolates were resistant to Ceporex and Ampicillin. In this study, females were the most affected with UTI and the most common organisms were E. coli and Klebsiella spp. It is therefore important to consider the sensitivity pattern of uropathogens to local antibiotics when it comes to the selection of treatment regimen for urinary tract infection.
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