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Production and Application of Microbial Surfactant from Cassava Wastewater
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Volume 2, 2015
Issue 4 (July)
Pages: 85-89   |   Vol. 2, No. 4, July 2015   |   Follow on         
Paper in PDF Downloads: 46   Since Aug. 28, 2015 Views: 1792   Since Aug. 28, 2015
John U. S., Chemical Engineering Department, Nnamdi Azikiwe University, Awka, Nigeria.
John M. C., Chemical Engineering Department, Nnamdi Azikiwe University, Awka, Nigeria.
Yeast Candida Bombicola is described to synthesize sophorolipids. Sophorolipids biosurfactant is categorized under the family of the glycolipid molecules with surface tension lowering capacities. These biosurfactants offer an environmental friendly alternative for the petrochemical derived surfactants used in various sectors and attract quite some industrial attention due to high yields when cultivated with Yeast Candida bombicola. On top of their surface lowering properties, sophorolipids display several interesting biological activities, allowing applications in the cosmetics, pharmaceutical and medical field. Sophorolipids production processes were outlined as well as recent findings on the biosynthetic pathway. From this study over 300g/l of sophorolipids was produced and 65% substrate conversion was achieved by the action of yeast candida bombicola on Cassava wastewater. Recent and novel applications of sophorolipids are summarized.
Microbial Surfactant, Soropholipids, Yeast Candida Bombicola, Cassava Wastewater
Develter D, Renkin M, Jacobs I. Detergent compositions. European patent EP1445302; 2007.
Marchal R, Lemal J, Sulzer C, Davila AM. Production of sophorolipid acetate acids from oils or esters. US patent US 5900366; 1999.
Futura T, Igarashi K, Hirata Y. Low-foaming detergent compositions. World Patent WO 03/002700; 2002.
Shah V, Doncel G.F, Seyoum T, Eaton K.M, Zalenskaya I, Hagver, R. Sophorolipids, microbial glycolipids with anti-human immunodeficiency virus and sperm-immobilizing activities. Antimicrob Agents AndChe mother 2005; 49: 4093–100.
Lang S, Katsiwela E, Wagner F. Antimicrobial effects of biosurfactants. FettWiss Technol-Fat SciTechnol 1989;91:363–6.
Bluth MH, Kandil E, Mueller CM, Shah V, Lin YY, Zhang H, et al. Sophorolipids block lethal effects of septic shock in rats in a cecal ligation and puncture model of experimental sepsis. Crit Care Med 2006;34:188–95.
Spencer JFT, GorinPAJ, Tulloch AP. Torulopsis bombicola sp. n. Antonie VanLeeuwenhoek 1970;36:129–33.
Rosa CA, Lachance MA, Silva JOC, Teixeira ACP, Marini MM, Antonini Y, et al. Yeast communities associated with stingless bees. FEMS Yeast Res 2003; 4:271–5.
Rosa CA, Lachance MA. The yeast genus Starmerella gen. nov.and Starmerella bombicola sp. nov., the teleomorph of Candida bombicola (Spencer, Gorin&Tullock) Meyer & Yarrow. Int J Syst Bacteriol 1998;48:1413–7.
Ohama T, Suzuki T, Mori M, Osawa S, Ueda T, Watanabe K, et al. Non universal decoding of the leucine codon cug in several Candida species. Nucleic Acids Res 1993; 21:4039–45.
Pesole G, Lotti M, Alberghina L, Saccone C. Evolutionary origin of non universalcug(ser) codon in some Candida species as inferred from a molecular phylogeny. Genetics 1995;141:903–7.
Tuite MF, Santos MAS. Codon reassignment in Candida species: an evolutionary conundrum. Biochimie 1996;78:993–9.
Hommel R, Stuwer O, Stuber W, Haferburg D, Kleber HP. Production of water-soluble surface-active exolipids by Torulop sisapicola. Appl Microbiol Biotechnol 1987;26:199–205
Smyth TJ, Perfumo A, Marchant R, Banat IM, Chen ML, Thomas RK, et al. Directed microbial biosynthesis of deuterated biosurfactants and potential future application to other bioactive molecules. Appl Microbiol Biotechnol 2010;87:1347–54.
Saerens K, Van Bogaert INA, Soetaert W, VandammeEJ. Production of glucolipids and specialty fatty acids from sophorolipids by Penicillium decumbensnaringinase: optimization and kinetics. Biotechnol J 2009;4: 517–24.
Van Bogaert INA, Saerens K, De Muynck C, Develter D, Soetaert W, Vandamme EJ. Microbial production and application of sophorolipids. Appl Microbiol Biotechnol 2007;76:23–34.
Daverey, A. Pakshirajan, K. Sangeetha, P. Sophorolipids Production by Candida Bombicola using Synthetic Dairy Wastewater. World Academy of Science, Engineering and Technology, 2009-03-26, Vol:3
Naim Kosaric, Fazilet Vardar Sukan, Biosurfactants: Production and Utilization—Processes, Technologies, and Economsics, CRC Press, 3 Nov. 2014.
Kumar DVR, Kasture M, Prabhune AA, Ramana CV, Prasad BLV, Kulkarni AA. Continuous flow synthesis of functionalized silver nanoparticles using bifunctional biosurfactants. Green Chem 2010;12:609–15.
Singh S, D’Britto V, Prabhune A A, Ramana CV, Prasad BLV. Cytotoxic and genotoxic assessment of glycolipid-reduced and -capped gold and silver nanoparticles. New J Chem 2010;34:294–301.
Singh S, Patel P, Jaiswal S, Prabhune AA, Ramana CV, Prasad BLV. A direct method for the preparation of glycolipid-metal nanoparticle conjugates: sophorolipids as reducing and capping agents for the synthesis of water redispersible silver nanoparticles and their antibacterial activity. New J Chem 2009; 33: 646–52.
Baccile N, Nassif N, Malfatt IL, Van Bogaert INA, Soetaert W, Babonneau F. Sophorolipids: a yeast-derived glycolipid as greener structure directing agents for self-assembled nanomaterials. Green Chem 2010;12:1564–7.
Lo CM, JuLK. Sophorolipids-induced cellulase production in cocultures of Hypo-creajecorina Rut C30 and Candida bombicola. Enzyme Microb. Technol 2009;44:107–11.
Gross RA, Shah V. Sophorolipids as protein inducers and inhibitors in fermentation medium/World patent WO2007073371; 2007.
Inoue S, Miyamoto N. Process for producing a hydroxyl fatty acid ester. US patent US4201844; 1980.
Mager H, Röthlisberger R, Wzgner F. Use of sophorolse-lipid lactone for the treatment of dandruffs and body odeur. European patent EU0209783; 1987.
Isoda H, Kitamoto D, Shinmoto H, Matsumura M, Nakahara T. Microbial extracellular glycolipid induction of differentiation and inhibition of the protein kinase C activity of human promyelocytic leukemia cell line HL60. Biosci. Biotechnol. Biochem 1997;61:609–14.
Chen J, Song X, Zhang H, Qu, Y.B, Miao J.Y. Sophorolipid produced from the new yeast strain Wicker hamiella domercqiae induces apoptosis in H7402 human liver cancer cells. Appl Microbiol Biotechnol 2006;72:52–9.
Fu SL, Wallner S.R, Bowne W.B, Hagler M.D, Zenilman ME, Gross R, et al. Sophorolipids and their derivatives are lethal against human pancreatic cancer cells. J Surg Res 2008;148:77–82.
Gross RA, Shah V. Anti-herpes virus properties of various forms of sophorolipids. World patent WO2007US63701; 2007.
Sleiman J.N, Kohlhoff S.A, Roblin PM, Wallner S, Gross R, Hammerschlag M.R. Sophorolipids as antibacterial agents. Ann Clin Lab Sci 2009;39:60–3.
Vakil H, Sethi S, Fu S, Stanek A, Wallner S, Gross R. Sophorolipids decrease pulmonary inflammation in amouse asthma model. Lab Invest 2010; 90: 1750.
Desai, J.D., Banat, I.M. Microbial production of surfactants and their commercial potential. Microbiol. Mol. Biol. Rev. 1997, 61, 47– 64.
Banat, I.M., Makkar, R.S., Cameotra, S.S. Potential commercial applications of microbial surfactants. Appl. Microbiol. Biotechnol. 2000. 53, 495–508.
Mercade M.E, Manresa M.A. The use of agroindustrial byproducts for biosurfactant production. Journal of American Oil Chemical Society. 1994;71:61-64.
Makkar R.S, Cameotra S.S. Biosurfactant production by microorganisms on unconventional carbon sources-a review. Journal of Surfactant Detergent. 1999;2:237-241.
Marcia Nitschke, Glaucia Maria Pastore. Production and properties of a surfactant obtained from Bacillus subtilis grown on cassava wastewater Yeast Candida Bombicola, Bioresource Technology 97 (2006) 336–341.
Achlesh Daverey, Kannan Pakshirajan. Sophorolipids from Candida bombicola using mixed hydrophilic substrates: Production, purification and characterization. Colloids and Surfaces B: Biointerfaces 79 (2010) 246–253.
Reetika_Gupta. Biosynthesis of novel Sophorolipids using Candida bombicola ATCC 22214: Characterization and applications. Thesis, June 2012, 26.
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