Background: Unfortunately, many women will experience short- or long-term mood disturbances postpartum. Post-partum depression can transform this period into a nightmare. Objectives: To determine the prevalence of post-partum depression among women during post-partum follow up and to determined risk factorsof post partum depression. Patients and Methods: It was cross-sectional and hospital based studyconducted in Khartoum Maternity hospital, during one year (March 2012 – March 2013). A total of 500women were chosen as proportion of total number of women attending the refer clinic for postpartum follow up. A systemic random sampling technique was used to select the study sample. A detailed and structured questionnaire was filled directly by women. Results: The mean ±SD of age was 31.5 + 3.1 years. Fifty five (11.0%) were had depression, while 445 (89.0%) were not. Sixteen (3.2%) had mild form, 30 (6.0%) had moderate and 9 (1.8%) had severe depression.The study find significant statistical association between depression and the following variables: p value < 0.05, age, parity, unwanted pregnancy, number of miscarriages, loss of husband support and personal or family history of psychiatric illness.Conclusion: The present study concluded that almost 11.0% of these women are experiencing moderate levels of depressive symptoms. As well, there are implications for practice, theory, policy, and knowledge translation.

Depression, Prevalence, Risk Factors, Post-Partum