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The Effect of Gestational Diabetes on Placental Shape in Sudanese: A Comparative Study
Current Issue
Volume 5, 2018
Issue 3 (September)
Pages: 12-15   |   Vol. 5, No. 3, September 2018   |   Follow on         
Paper in PDF Downloads: 17   Since Feb. 13, 2019 Views: 866   Since Feb. 13, 2019
Mohamed Nouh Mohamed Ahmed, Faculty of Medicine, Alzaeim Alazhari University, Khartoum, Sudan.
Sami Arbab Saeed, Faculty of Medicine, Alzaeim Alazhari University, Khartoum, Sudan.
Muhammad Alamin Ahmed Abdalla, Faculty of Medicine, Alzaeim Alazhari University, Khartoum, Sudan.
Ali Osman Ali Mansour, Faculty of Medicine, Alzaeim Alazhari University, Khartoum, Sudan.
Zeinab Eltayeb Elfaki, Faculty of Medicine, Alzaeim Alazhari University, Khartoum, Sudan.
Saadeldin Ahmed Idris, Faculty of Medicine, Alzaeim Alazhari University, Khartoum, Sudan.
The placenta is a new organ formed in the uterus during pregnancy, creating a vital connection between the developing baby and the mother. Gestational diabetes may cause some structural alterations of placenta. In the aiming to find out the effect of Gestational diabetes on placental shape in a singleton pregnancy, A case control prospective study was carried out in Omdurman Maternity Hospital, Khartoum (January 2015 ¾ September 2017), after due approval from institutional research committee, Alzaeim Alazhari University. The subjects were mothers who delivered their babies in the hospital. Cases were selected randomly, and divided in two groups: group A consisted of mothers having normal, uncomplicated pregnancy, group B consisted of mothers whose pregnancies were complicated by gestational diabetes mellitus. The statistical methods used were Chi-square test and Student's t test. A total of 385 placentae were collected, 128 were gestational diabetic placentae (Group A) and 257 were normal placentae (group B). In the current study gestational diabetes showed no effect on shape in normal and gestational placentae (P. value 0.659). This study updates the data related to the effect of gestational diabetes on the shape of placenta and confirmed that the gestational diabetes has no effect on placental shape.
Placenta, Gestational Diabetes Mellitus, Normal Pregnancy, Placental Shape, Parity, Body Mass Index (BMI)
Hayward C, Lean S, Sibley C, Jones R, Wareing M, Greenwood S, Dilworth M. Placental adaptation: What can we learn from birth weight: Placental weight ratio? Physiol., 2016; 7:1-13.
Elmahdi EM, Abdul Rahman IEM, Mukhtar EA. Pattern of Diabetes M ellitus in the Sudan: Top Geogr Med., 1989; 41 (4):353-7.
Teasdale F. Histomorphometry of the human placenta in Class B diabetes mellitus. Placenta, 1983; 4 (1):1-12.
Elshennawy TMA. Effect of gestational diabetes on gross morphology, histology and histochemistry of human placenta. Endocrinol Metab Syndr., 2016; 5: 227.
Tiwari V, Manik P, Pankaj AK, Pandey A, Rani A. Study of shape of placenta and its relation to placental weight in normal and diabetic pregnancies. International Journal of Multidisciplinary Research and Development, 2015; 2 (9): 666-669.
Cunningham FG, Leveno KJ, Bloom SL, Hauth JC, Gilstap LC, Wenstrom KD. Williams obstetrics in Implantation, embyogenesis and placental development. 22nd ed. 1930. New York: Mc Graw –Hill. 22 : 828-829.
Bernischke K, Kaufmann P, Baergen R. (Eds.) Pathology of the human placenta (5th ed) 2006. New York, NY. P. 116-154.
Abdelghany AH, Eissa TM, Idris S. Study of the ultrastructure of the placenta in gestational Diabetes mellitus. Int J Anat Var., 2018; 11 (1):4-10.
Xiaoli L, Liying Z, Hao C. Effects of maternal age on pregnancy and delivery outcomes. Chinese Journal of Medical Science, 2014; 94 (25): 1984-1988.
Roum EMS, Haavaldsen C, Tanbo TG, Eskild A. Paternal age, placental weight and placental to birth weight ratio: a population-based study of 590 835 pregnancies. Human Reproduction, 2013; 28 (11):3126–3133.
Asgharnia M, Esmailpour N, Poorghorban M, Atrkar-Roshan Z. Placental weight and its association with maternal and neonatal characteristics. Acta Medica Iranica, 2008; 46 (6):467-472.
Erbil N, Toprak N, Açıkgöz Ö, Gelen S, Arık N. The Relationship between Maternal, Placental and Newborn Parameters. Middle Black Sea Journal of Health Science, 2015; 1 (1):11-18.
Saini P, Pankaj JP, Jain A, Agarwal GC. Effect of gestational diabetes mellitus on gross morphology of placenta: A comparative study. Int J Anat Res., 2015; 3 (1):889-94.
Arshad R, Karim N, Hasan JA. Effects of insulin on placental, fetal and maternal outcomes in gestational diabetes mellitus. Pak J Med Sci., 2014; 30 (2):240-244.
Cypryk K, Szymczak W, Czupryniak L, Sobczak M, Lewiński A. Gestational diabetes mellitus - an analysis of risk factors. Endokrynologia Polska, 2008; 59 (5):393-397.
Jang HC, Min HK, Lee HK, Cho NH, Metzger BE. Short stature in Korean women: a contribution to the multifactorial predisposition to gestational diabetes mellitus. Diabetologia, 1998; 41:778-83.
Jain A, Jain R, Baweja S. Variability of the human placental shapes in normal and pre-eclamptic pregnancies and its effects on placental and foetal outcomes. J. Evolution Med. Dent. Sci., 2016; 5 (80):5929-5932.
Coustan DR. Gestational diabetes In: Management of high risk pregnancy. Blackwell Science England, 1999; 4:261-9.
Anjum A, Suseelamma D, Saritha S, Ramani TV, Jyothi DN. Study of morphological variations of 50 placentae with umbilical cords and its developmental relevance. Int J Anat Res., 2015; 3 (3):1259-66.
Raghunath G, Shenoy VV. Clinically relevant morphology and morphometry of Placenta. Journal of Clinical and Diagnostic Research, 2011; 5 (2):282-286.
Ashfaq M, Janjua MZ, Channa MA. Effect of gestational diabetes and maternal hypertension on gross morphology of placenta. J Ayub Med Coll Abbottabad, 2005; 17 (1):44-47.
Akhter F, Banu LA, Ferdausi R. Effect of gestational diabetes mellitus on gross morphological structure of preterm placenta. Bangladesh Journal of Anatomy, 2010; 8 (1):34-38.
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