Welcome to Open Science
Contact Us
Home Books Journals Submission Open Science Join Us News
Lactating Adenoma of the Breast a Diagnostic Difficulty in Pregnancy and Rewarding Natural History during Lactation: A Case Report and Review of Literature
Current Issue
Volume 1, 2014
Issue 1 (February)
Pages: 13-16   |   Vol. 1, No. 1, February 2014   |   Follow on         
Paper in PDF Downloads: 13   Since Aug. 28, 2015 Views: 1652   Since Aug. 28, 2015
Aamir A. Hamza , Department of General Surgery,College of Medicine and Health Sciences, University of Bahri, Khartoum, Sudan.
Saadeldin A. Idris , Department of General Surgery, Faculty of Medicine, Alzaeim Alazhari University, Khartoum, Sudan.
Lactating adenoma of the breast is a very rare pathological condition. Usually occurs during pregnancy or lactation. Pathological diagnosis is difficult, because of the lactation changes during pregnancy and rarity of the condition. Herein we presented a 20-year-old Sudanese female with a left breast mass, firm in consistency, increasing in size rapidly with time. Fine needle aspiration cytology (FNAC) was done twice together with Tru-cut needle biopsy and all were inconclusive. Later on incisional biopsy was performed that led to resolution of the diagnostic dilemma and establishes the pathology of lactating adenoma. Bromocriptine mesilate tablet was started and soon discontinued as it causes severe nausea to the patient. Surgery was advised and patient refused the operation. During subsequent follow up, it increased dramatically after delivery to reach a maximum size of 15 x 10 cm. and then gradually regressed to reach 2 x 1 cm, eighteen months after delivery.
Breast lump, Lactation, Lactating Adenoma, Pregnancy
Choudhury M, Signal M. Lactating adenoma, cytomorphologic study with review of literature. Indian J Pathol Micobiol. 2001 Oct; 44(4):445-8.
Kemp B, Kushwaha A, Evans G, Hunt KK, Baker TPO, Lenert JT, Paker J. Lactating adenoma: A diagnosis of exclusion. Breast 2001 Sep-Oct; 7(5):354-7.
Priavadhana Rajan Prasaad. Fine needle aspiration cytologic diagnosis of lactating adenoma: Report of two Cases. J Clin Diagn Res. 2013 October; 7(10): 2417–2418. doi: 10.7860/JCDR/2013/5260.3544.
Saglam A, Can B. Coexistence of lactating adenoma and invasive ductal adenocarcinoma of the breast in a pregnant woman. J Clin Pathol 2005; 58:87–89. doi: 10.1136/jcp.2004.018275.
Amr SS, Sa’di AR, Ilahi F, Sheikh SS. The spectrum of breast diseases in Saudi Arab females: A 26 year pathological survey at Dhahran Health Center. Ann Saudi Med. 1995 Mar; 15(2):125-32.
Hertel BF, Zaloudek C, Kempson RL. Breast adenomas. Cancer 1976; 37:2891-2905.
kered James, John Bridger and Peter P. Anthony. Breast tumor of pregnancy (lactating adenoma) Journal of Pathology 1998; 156:37-44.
Manipadam MT, Jacob A, Rajnikanth J. Giant lactating adenoma of the breast. J. surg. case rep. 2010; 2010(9):8. doi: 10.1093/jscr/2010.9.8.
Mark E Reeves, Arnold Tabuenca. Lactating adenoma presenting as a giant breast mass. Surgery 2000; 127(5):586-588.
Magno S, Terribile D, Franceschini G, Fabbri C, Chiesa F, Leone A Di, Costantini M, Belli P, Masetti R. Early onset lactating adenoma and the role of breast MRI: A case report. Journal of Medical Case Reports 2009; 3:43-47. doi:10.1186/1752-1947-3-43.
Sumkin JH, PerroneAM, HarrisKM, Nath ME, Amortegui AJ, Weinstein BJ. Radiology. Lactating adenoma: US feature and literature review. 1998 Jan; 206(1):271-4.
Marla L Rosenfield Darling, Darrell N Smith, Esther Rhei, Christine M Denison, Susan C Lester, Jack E Meyer. Lactating Adenoma: Sonographic features. The Breast Journal 2000; 6(4):252-256.
AbidIrshad, Susan J Ackerman, Thomas L Pope, Christopher K Moses, Tihana Rumboldt, Beata Panzegrau. Rare Breast lesions: Correlation of imaging and histologic features with WHO classification. Radiographics 2008 Mar; 28(5): 1399-414.
Novo DB, Maygarden SJ, Shermer RW, Frable WJ. Fine needle aspiration of benign and malignant breast masses associated with pregnancy. Acta Cytol. 1991 Nov-Dec; 35(6):676-86.
Vesoulis Z, Kashkari S. Fine needle aspiration of secretory breast carcinoma resembling lactational changes. A case report. Actacutol. 1998 Jul-Aug; 42(4): 1032-6.
Open Science Scholarly Journals
Open Science is a peer-reviewed platform, the journals of which cover a wide range of academic disciplines and serve the world's research and scholarly communities. Upon acceptance, Open Science Journals will be immediately and permanently free for everyone to read and download.
Office Address:
228 Park Ave., S#45956, New York, NY 10003
Phone: +(001)(347)535 0661
Copyright © 2013-, Open Science Publishers - All Rights Reserved