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Precipitating Factors of Hepatic Encephalopathy Among Sudanese Patients with Liver Cirrhosis
Current Issue
Volume 2, 2015
Issue 4 (August)
Pages: 63-67   |   Vol. 2, No. 4, August 2015   |   Follow on         
Paper in PDF Downloads: 17   Since Sep. 7, 2015 Views: 2109   Since Sep. 7, 2015
Authors
[1]
Siddig Omer Handady, Department of Obstetrical and Gynecology, Imperial Hospital, Khartoum, Sudan.
[2]
Maiada Abbas Ahmed, Department of Internal Medicine, Khartoum North hospital, Khartoum, Sudan.
[3]
Amira Abbas Fadl, Department of Internal Medicine, Alribat University Hospital, Khartoum, Sudan.
[4]
Awad Ali M. Alawad, Department of Surgery, Faculty of Medicine, University of Medical Sciences and Technology, Khartoum, Sudan.
Abstract
Background: Hepatic encephalopathy is a challenging complication of advanced liver disease causing significant morbidity and mortality worldwide. Objective: To determine the precipitating factors of hepatic encephalopathy (HE) in Sudanese patients with liver cirrhosis. Methodology: It was cross sectional study, descriptive, prospective and hospital based study, conducted at Khartoum state hospitals in Sudan over a period of six months from November 2013 to April 2014. One hundred and twenty (n=120) adults, diagnosed cases of liver cirrhosis were included in this study. Results: Ninety one (n= 91, 75.8%) were male and twenty nine (29, 24.2 %) were females. The mean age was 50.23 years with STD ± 16.2. The common precipitating factors identified in this study were as follows, (n= 50,) (41.7%) had infection (n= 43,) (36.4%) had constipation, (n=33, 27.5%) had hypokalemia, (n=32, 26.7%) had hematemesis and Melina, (n=26, 21.7%) had hyponatremia, hepato-renal syndrome, hepatocellular carcinoma and recent excessive paracentesis were seen in (21.7%), (13.3%) and (11.7%) of patients respectively. Conclusion: This study concluded that most common precipitating factors of hepatic encephalopathy in our patients are infection, constipation electrolyte imbalance and upper gastrointestinal bleeding. These are potentially preventable and reversible.
Keywords
Liver Cirrhosis, Hepatic Encephalopathy, Precipitating Factors
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