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Assessment of the Quality of Life Among Thalassemia Patients in the Gaza Strip
Current Issue
Volume 7, 2020
Issue 1 (March)
Pages: 21-28   |   Vol. 7, No. 1, March 2020   |   Follow on         
Paper in PDF Downloads: 58   Since Jan. 13, 2020 Views: 1196   Since Jan. 13, 2020
Asmaa Abu-Muammar, European Gaza Hospital, Khan Yunis City, Ministry of Health, Gaza strip, Palestine.
Background: Thalassemia is the most common hemoglobin disorder in the world and thalassemia major and intermedia stand among the most severe forms. Quality of Life (QOL) has emerged as an important parameter for assessing the quality of health care of patients with thalassemia disease. The QOL of thalassemia patients in the Gaza Strip has not previously been studied. Objective: The objective of this study is to assess QOL among patients with thalassemia disease in Gaza Strip, using the Short Form-36 (SF-36) questionnaire. Design and Setting: Descriptive, analytical, cross-sectional study has been performed on 200 thalassemia patients aged 18 years or more on follow-up at two hematology centers; Al-Shifa Hospital and European Gaza Hospital, in 2014. After the participants’ socioeconomics, demographics and disease characteristics had been recorded, they filled out the SF-36 questionnaire and the relationship between various variables and the QOL score was evaluated. Results: The results showed that study participants had a medium perception level of QOL (mean score was 41.98, SD=19.24). The overall mean percentage for SF-36 domains scores ranged from 24.68% to 53.85%. The general health domain got the highest score with relative weight equaled 53.85%, the social function domain: 51.78%, the physical function domain: 50.62%, the bodily pain domain: 49.90%, the mental health domain: 33.19%, the vitality domain: 32.70%, the emotional role limitation: 31.88% and the lowest domain was physical role limitation with relative weight of 24.68%. Conclusion: The findings demonstrated that, patients with thalassemia disease had a medium perception level about their QOL. The lowest perception was observed in role limitation due to physical function, which led to restriction of work capacity. However, most of patients were satisfied with their general health, which led to buffering effect on their psychological status and QOL. Promoting psychosocial, social and financial support may help them to cope better with their chronic disease. Designing and implementing educational programs for nurses who work in hematology units might be positively reflected on patients' QOL.
Quality of Life, Thalassemia, Gaza Strip
De Sanctis, V., Roos, M., Gasser, T., Fortini, M., Raiola, G., & Galati, M. C. (2006). Impact of long-term iron chelation therapy on growth and endocrine functions in thalassaemia. J Pediatr Endocrinol, 19: 471-480.
Ghaffari, J., Vahidshahi, K., Kosaryan, M., Parvinnejad, N., Mahdavi, M., & Karami, H. (2008). Nitroblue tetrazolium test in patients with beta-thalassemia major. Saudi Med J. 29: 1601-1605.
World Health Organization (2006). WHOQOL-BREF. Research tools. [Online]. Available: https://www.who.int/substance_abuse/research_tools/whoqolbref/en/
Borgna-Pignatti, C., Rugolotto, S., De Stefano, P., Zhao, H., Cappellini, M. D., Del Vecchio, G. C., Romeo, M. A., Forni, G. L., Gamberini, M. R., Ghilardi, R., Piga, A., & Cnaan, A. (2004). Survival and complications in patients with thalassemia major treated with transfusion and deferoxamine. Haematologica, 89: 1187–1193.
Roy, T., & Chatterjee, S. C. (2007). The experiences of adolescents with thalassemia in West Bengal, India. Qual Health Res. 17 (1): 85-93.
Origa, R. (2017). β-Thalassemia. Genet Med 19, 609–619
Premawardhana, A. P., Mudiyanse, R., De Silva, S. T., Jiffry, N., Nelumdeniya, U., de Silva, U., Oliveri, N. F. (2019). A nationwide survey of hospital-based thalassemia patients and standards of care and a preliminary assessment of the national prevention program in Sri Lanka. PloS one, 14 (8), e0220852.
Yu, U., Chen, L., Wang, X. et al. (2019). Evaluation of the vitamin D and biomedical statuses of young children with β-thalassemia major at a single center in southern China. BMC Pediatr 19, 375.
Aljeesh, YI. Quality of Life among Thalassemia Children Patients in the Gaza Strip. American Journal of Nursing Science. Vol. 5, No. 3, 2016, pp. 106-113
McHorney, C. A., Ware, J. E., Raczek, A. E. (1993). The MOS 36-item short-form health survey (SF-36): II. Psychometric and clinical tests of validity in measuring physical and mental health constructs. Med Care. 31 (3): 247-63.
Diaz-Buxo, J. A., Lowrie, E. G., Lew, N. L., Zhang, H., & Lazarus, J. M. (2000). Quality-of life evaluation using Short Form 36: comparison in hemodialysis and peritoneal dialysis patients. Am J Kidney Dis. 35 (2): 293-300.
Coons, S. J., Alabdulmohsin, S. A., Draugalis, JL. R., & Hays, R. D. (1998). Reliability of an Arabic version of the RAND-36 health survey and its equivalence to the US-English version. Medical care, 428-432.
Sabbah, I., Drouby, N., Sabbah, S., Retel-Rude, N., & Mercier, M. (2003). Quality of life in rural and urban populations in Lebanon using SF-36 Health Survey. Health and Quality of Life Outcomes, 1: 30.
Ware, J. E. (1993). SF-36 health survey: manual and interpretation guide. The Health Institute, New England Medical Center.
Brazier, E., Harper, R., Jones, N. M., O'Cathain, A., Thomas, K. J., Usherwood, T., & Westlake, L. (1992). Validating the SF-36 health survey questionnaire: new outcome measure for primary care. BMJ, 305: 160-164.
Eljedi A and Nofal M (2014) Health-Related Quality of Life and its Influencing Factors among Breast Cancer Patients in Palestine. J Womens Health, Issues Care 3: 5.
Luzon, F. (2008). Quality of Life among rehabilitated stroke survivors in Gaza Strip. Un-published thesis: The Islamic University of Gaza. Palestine.
Elayyan, W. (2007). Quality of life among Hypertensive Patients Attending Governmental and UNRWA Clinics. Master Thesis. Al-Quds University. Palestine.
Bart, O., Myrra, J., Vernooij, D., Egbert, S., Berna, V., Maria, E., Muijsenbergh, V. and Richard, P. (2002). Problems to discuss with cancer patients in palliative care: a comprehensive approach. Patient Education and Counseling, 47 (3): 195-204.
Platania, S., Gruttadauria, S., Citelli, G., Giambrone, L., & Di Nuovo, S. (2017). Associations of Thalassemia Major and satisfaction with quality of life: The mediating effect of social support. Health psychology open, 4 (2), 2055102917742054. doi: 10.1177/2055102917742054
Mettananda, S., Pathiraja, H., Peiris, R. et al. (2019). Health related quality of life among children with transfusion dependent β-thalassaemia major and haemoglobin E β-thalassaemia in Sri Lanka: a case control study. Health Qual Life Outcomes 17, 137
Yasmeen, H., Hasnain, S. (2018). Quality of Life of Pakistani Children with β-Thalassemia Major. Hemoglobin.42 (5-6): 320-325.
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