Welcome to Open Science
Contact Us
Home Books Journals Submission Open Science Join Us News
Haematological Changes in under Five Children Suffering from Diarrhoea in Elele Community
Current Issue
Volume 2, 2014
Issue 3 (June)
Pages: 25-28   |   Vol. 2, No. 3, June 2014   |   Follow on         
Paper in PDF Downloads: 15   Since Aug. 28, 2015 Views: 2343   Since Aug. 28, 2015
Authors
[1]
Ikechukwu R. A. Nnadozie, Dept. of Parasitology/Microbiology, Imo State University Teaching Hospital Orlu, Nigeria.
[2]
Fredrick C. Anolue, Dept. of Obstetrics and Gynaecology, Imo State University Teaching Hospital Orlu, Nigeria.
[3]
Godfrey I. Eberendu, Dept. of Paediatrics, Imo State University Teaching Hospital Orlu, Nigeria.
[4]
Christiana N. Anyanwu, Dept. of Pharmacy, Federal Medical Centre Owerri, Nigeria.
[5]
Damian C. Ukaji, Dept. of Microbiology/Haematology and Blood Transfusion, Madonna University Elele, Nigeria.
[6]
Anslem O. Ajugwo, Dept. of Microbiology/Haematology and Blood Transfusion, Madonna University Elele, Nigeria.
Abstract
Diarrhoea is the passage of loose or watery stool more frequently than normal, that develops suddenly as a result of irritation of large intestine by food residues, which moved too quickly through the large intestine and caused by many organisms mainly viral, bacterial and protozoan. This study examined the haematological changes that occurred in under five children suffering from acute diarrhoea in Elele Community. Samples were collected from 25 under five children suffering from acute diarrhoea and compared with another 25 samples from children without diarrhoea. The samples were analysed for Packed cell volume (PCV), Haemoglobin estimation (Hb), Total white blood cell (WBC) and Erythrocyte sedimentation rate (ESR) using standard manual methods. From the results obtained, there was significant increase (p<0.05) in PCV while Hb and ESR recorded significant decrease (p<0.05). These changes reflect dehydration and anaemic conditions. The changes were more marked in males than females. In children under five, diarrhoea affects haemostatic parameters.
Keywords
Diarrhoea, Watery Stool, Children, Dehydration, Haemostatic, Elele
Reference
[1]
Adimora, G. N., Ikefuna, A. N. and Ilechukwu, G. (2011). Home management of childhood diarrhea:need to intensify campaign. Nigerian Journal of Clinical Practice. 14 (2): 237 – 241.
[2]
Cooke, M. L. (2010). Causes and management of Diarrhoea in children in clinical setting. S. Afr. J. Clin. Nutr. 23 (1): S42 – S46.
[3]
Dupont, H. (2012). Guidelines on acute in-fectious Diarrhea in adults. Am. Astroenterol. 92: 19
[4]
Barwick, R., Levy, D. and Craun, C. (2010). Surveil-lance for waterborne disease outbreaks. Morbid Mortal Weekly Report. 49: 1 – 35.
[5]
Synder, J. and Merson, M. (1982). The magnitude of the global problem of acute diarrhea diseases: a review of active surveillance data. Bull. WHO, 605 – 613.
[6]
Abu-Saeed, K. , Olakunle, J. M., Odili, V. U. and Abu-Saeed, M. B. (2012). Assessment of mother’s knowledge of home management of childhood diarrhea in a Nigerian setting. Int. J. Pharm. Res. Biosci. 1(4): 168 – 184.
[7]
Ukaegbu, A. U. D. and Ukaegbu, P. O. (2010). Mother’s knowledge, perceptions and practices of home based management of childhood diarrhea in a rural community in Anambra State, Nigeria. Nig. J. Nutr. Sci. 31 (2): 8 – 10.
[8]
Ojuawo, A. and Oyaniyi, A. T. (1993). Treatment of diarrhea by proprietary medicine vendors. Nig. J. Paediatr. 20; 41 – 45.
[9]
Uwaezuike, S. N., Tagbo, B. N. and Okoro, B. A. (2003). Knowledge and utilization of oral rehydration therapy (ORT) among mothers in Enugu, Nigeria: a facility survey. Orient J. Med. 15: 45 – 48.
[10]
Uwaegbute, A. C., Ene-Obong, H. N., Onwurah, A. and Amazigo, U. V. (1994). Influence of perceptions on treatment practices for diarrhea in two Igbo communities in Nigeria. Nig. J. Paediatr. 21(suppl):99 – 110.
[11]
Ene-Obong, H. N., Iroegbu, C. U. and Uwaegbute, A. C. (2000). Perceived causes and management of diarrhea in young children by market women in Enugu State, Nigeria. J. Health Popul. Nutr. 18(2): 97 – 102.
[12]
Binder, H. and Powell, D. (2009). Bacterial enterotoxins and diarrhea. 23: 1582.
[13]
Cheesbrough, M. (2000). Haematological tests. In: District laboratory practice in tropical countries. Part 2 Cambridge University Press U.K., 297.
[14]
Todd, W. T., Lockwood, D. N. and Sundar, S. (2006). Infectious diseases. In: Davidson’s Principle and practice of Medicine. 20th edition. Boon et al (editors). Churchill Livingstone, Edinburgh. P 293.
[15]
Wijewardene, K., Fonseka, P. and Wijayasiri, W.A. (1992). Risk factors contributing to acute diarrhoeal disease in children below five years. Ceylon Med. J. 37(4):116-9.
[16]
Kosek, M., Bern, C. and Guerrant, R. L. (2003). The global burden of diarrhoeal disease, as estimated from studies published between 1992 and 2000. Bull World Health Organ. 81 (3): 197-204.
[17]
Bellemare, S. Hartling, L. et al.(2006). Oral rehydration versus intravenous therapy for treating dehydration due to gastroenteritis in children: a meta-analysis of randomised controlled trials. The Cochrane Library, issue 4.
[18]
Brown, K. H.(2003). Diarrhea and Malnutrition. J. Nutr. 133 (1): 328S-332S.
[19]
Gracey, M. (1985). Diarrhoeal disease and malnutrition. Churchill Livingstone, Edinburgh,
[20]
Jinadu, M. K., Olusi, S. O., Agun, J. I. and Fabiyi, A. K. (1991). Childhood diarrhoea in rural Nigeria. I. Studies on prevalence, mortality and socio-environmental factors. J Diarrhoeal Dis Res. 9(4):323-7.
[21]
Teklemariam, S., Getaneh, T. and Bekele, F. (2000). Environmental determinants of diarrheal morbidity in under-five children, Keffa-Sheka zone, south west Ethiopia. Ethiop Med. J. 38(1):27- 34.
[22]
Molbak, K. (2000). The epidemiology of diarrheal diseases in early childhood: A review of community studies in Guinea-Bissau. University of Copenhaghen.
Open Science Scholarly Journals
Open Science is a peer-reviewed platform, the journals of which cover a wide range of academic disciplines and serve the world's research and scholarly communities. Upon acceptance, Open Science Journals will be immediately and permanently free for everyone to read and download.
CONTACT US
Office Address:
228 Park Ave., S#45956, New York, NY 10003
Phone: +(001)(347)535 0661
E-mail:
LET'S GET IN TOUCH
Name
E-mail
Subject
Message
SEND MASSAGE
Copyright © 2013-, Open Science Publishers - All Rights Reserved