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Simple UV Spectrophotometric Assay of Glimepride
Current Issue
Volume 2, 2014
Issue 4 (August)
Pages: 94-97   |   Vol. 2, No. 4, August 2014   |   Follow on         
Paper in PDF Downloads: 15   Since Aug. 28, 2015 Views: 5960   Since Aug. 28, 2015
Authors
[1]
Safila Naveed, Jinnah University for Women, Karachi, Pakistan.
[2]
Hina Qamar, Jinnah University for Women, Karachi, Pakistan.
[3]
Wardha Jawaid, Jinnah University for Women, Karachi, Pakistan.
[4]
Urooj Bokhari, Jinnah University for Women, Karachi, Pakistan.
Abstract
Glimepride belongs to sulfonylurea oral anti diabetic. A efficient least time consuming and simple spectrophotometric method for the assay of Glimepride has been used. The assay is based on the ultraviolet UV absorbance maxima at about 200nm wavelength of Glimepride using water as solvent. A sample of drug was dissolved in water to produce a solution containing Glimepride. Similarly, various dilutions were made. The absorbance of sample preparation was measured at 200nm against the solvent blank and the assay was determined. In our study a simple and quick assay method using U.V spectrophotometer has been used. The assay is based on measuring the absorbance of formulation of Glimepride dilutions at the wavelength of 200 nm. Four different dilutions of 50ppm, 25ppm, 12.5ppm and 6.25ppm is prepared and their percent assay is calculated.
Keywords
Glimepride, Assay, UV Spectrophotometry
Reference
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[9]
Huma Dilshad, Safila Naveed and Ghulam Sarwar (2014) Simple spectrophotometric assay of available brands of Acetaminophen tablets and their comparative study Journal of pharmacy and pharmaceutical sciences Volume 2, Issue 1,1-4
[10]
Safila Naveed, Fatima Qamar, Ghulam Sarwer., (2014) Percentage assay of metformin in different medium using UV- spectrophotometer BPJ0000130 - World Research Journal of Organic Chemistry Volume : 2 Issue : 1, 12-14 ISSN: 2320-3374 & E-ISSN: 2320-5679, http://www.bioinfopublication.org/jouarchive.php?opt=&jouid=BPJ0000130
[11]
Safila Naveed (2014) Simple UV spectrophotometric assay of Atorvastatin API formulation and their comparative study, Global Journal of Medical Research .14(2):35-38. https://globaljournals.org/GJMR_Volume14/4-Simple-UV-Spectrophotometric-Assay.pdf
[12]
Safila Naveed and Fatima Qamar (2014) A simple assay of Esomeprazole Using UV spectrophotometer The Global Journal of Pharmaceutical Research (TGJPR) 3(2); 1921-25, http://www.tgjpr.com/view-article.php?id=3433
[13]
Safila Naveed and Fatima Qamar (2014) Simple UV spectrophotometric assay of Mefenamic acid International Journal of Pharma Sciences and Research (IJPSR) ,5(7):364-366 .http://www.ijpsr.info/ijpsr-v5n7.php
[14]
Safila Naveed, Shabana Naz Shah, Fatima Qamar , Nimra Waheed, and Safeena Nazeer, (2014) simple uv spectrophotometric assay of new formulation gentamycin J App Pharm Vol. 6; Issue 4: 407-410
[15]
Safila Naveed, Shabana Naz Shah, Fatima Qamar , Nimra Waheed, and Safeena Nazeer, (2014) Simple UV spectrophotometric assay of Lincomycin, IJPRDD, 1 (2),10-12.
[16]
Safila Naveed* and Amber Nawab (2014) Assay of LVFX (levofloxacin) in different formulation by UV spectroscopy IJPRDD, 1 (2), 13-16.
[17]
Safila Naveed and Fatima Qamar (2014) Simple UV spectrophotometric assay of Metronidazole Open Access Library Journal, 1: e615:1-4. http://dx.doi.org/10.4236/oalib.1100615
[18]
Huma Dilshad, Safila Naveed and Baqir Naqvi (2013) Assay of new formulations of isosorbide mononitrate by using uv spectrophotometer : BPJ0000115 - World Research Journal of Medicine Volume : 1 Issue : 1, pg9-10.
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