Clinical Presentations in Preeclamptic Women Attending Elnihoud Teaching Hospital
Preeclampsia is the most common hypertensive disorders of pregnancy which is an idiopathic multisystem disorder that contributes greatly to the maternal morbidity and mortality. To evaluate the clinical presentations in preeclamptic women attending Elnihoud Teaching Hospital and to compare the findings between severe and mild cases. This study was descriptive cross sectional study; carried out in Elnihoud Teaching Hospital. A total of forty tow pregnant women were included in this study. They were selected from the Wards of the Hospital at admission before starting treatment. Clinical examination was done after taking of permission from every participants. The study revealed significant elevation in the clinical presentation of headache (p-value = < 0.0001), blurring vision (p-value = < 0.0001), epigastric pain (p-value = < 0.0001), RHP (p-value = 0.006), breathlessness (p-value = 0.015) abdominal pain (p-value = 0.002), tachycardia (p-value = 0.010), less than date fundal level (p-value = 0.005), hyper reflexes (p-value = 0.007), lower limbs edema (p-value = 0.009), and papillodema (p-value = 0.002) among sever preeclamptic patients compared to mild cases. Elevation in clinical presentations associated with preeclamptic women might reflect the severity of the disease.
Preeclampsia, Hypertension, Breathlessness, Papillodema
Gongora, M. C. and Wenger, N. K. (2015) Cardiovascular Complications of Pregnancy Int J Mol Sci Volunme (10): 23905-23928.
Lindheimer, M. D., Taler, S. J. and Cunningham, F. G. (2010) Hypertension in pregnancy J Am Soc Hypertens Volunme (2): 68-78.
Say, L., Chou, D., Gemmill, A., Tuncalp, O., Moller, A. B., Daniels, J., Gulmezoglu, A. M., Temmerman, M. and Alkema, L. (2014) Global causes of maternal death: a WHO systematic analysis Lancet Glob Health Volunme (6): e323-333.
Folic, M., Folic, N., Varjacic, M., Jakovljevic, M. and Jankovic, S. (2008) Antihypertensive drug therapy for hypertensive disorders in pregnancy Acta Med. Median Volunme (47): 65–72.
Moussa, H. N., Arian, S. E. and Sibai, B. M. (2014) Management of hypertensive disorders in pregnancy Womens Health (Lond) Volunme (4): 385-404.
Chaiworapongsa, T., Chaemsaithong, P., Yeo, L. and Romero, R. (2014) Pre-eclampsia part 1: current understanding of its pathophysiology Nat Rev Nephrol Volunme (8): 466-480.
Practice, A. C. o. O. (2002) ACOG practice bulletin. Diagnosis and management of preeclampsia and eclampsia. Number 33, January 2002. American College of Obstetricians and Gynecologists Int J Gynaecol Obstet Volunme (1): 67-75.
Grand'Maison, S., Pilote, L., Okano, M., Landry, T. and Dayan, N. (2016) Markers of Vascular Dysfunction After Hypertensive Disorders of Pregnancy: A Systematic Review and Meta-Analysis Hypertension Volunme (6): 1447-1458.
English, F. A., Kenny, L. C. and McCarthy, F. P. (2015) Risk factors and effective management of preeclampsia Integr Blood Press Control Volunme 7-12.
Fisher, S. J. (2015) Why is placentation abnormal in preeclampsia? Am J Obstet Gynecol Volunme (4 Suppl): S115-122.
Gathiram, P. and Moodley, J. (2016) Pre-eclampsia: its pathogenesis and pathophysiolgy Cardiovasc J Afr Volunme (2): 71-78.
Hanna, J., Goldman-Wohl, D., Hamani, Y., Avraham, I., Greenfield, C., Natanson-Yaron, S., Prus, D., Cohen-Daniel, L., Arnon, T. I., Manaster, I., Gazit, R., Yutkin, V., Benharroch, D., Porgador, A., Keshet, E., Yagel, S. and Mandelboim, O. (2006) Decidual NK cells regulate key developmental processes at the human fetal-maternal interface Nat Med Volunme (9): 1065-1074.
Fukui, A., Yokota, M., Funamizu, A., Nakamua, R., Fukuhara, R., Yamada, K., Kimura, H., Fukuyama, A., Kamoi, M., Tanaka, K. and Mizunuma, H. (2012) Changes of NK cells in preeclampsia Am J Reprod Immunol Volunme (4): 278-286.
Tessier, D. R., Yockell-Lelievre, J. and Gruslin, A. (2015) Uterine Spiral Artery Remodeling: The Role of Uterine Natural Killer Cells and Extravillous Trophoblasts in Normal and High-Risk Human Pregnancies Am J Reprod Immunol Volunme (1): 1-11.
Burton, G. J., Woods, A. W., Jauniaux, E. and Kingdom, J. C. (2009) Rheological and physiological consequences of conversion of the maternal spiral arteries for uteroplacental blood flow during human pregnancy Placenta Volunme (6): 473-482.
Amaral, L. M., Cunningham, M. W., Jr., Cornelius, D. C. and LaMarca, B. (2015) Preeclampsia: long-term consequences for vascular health Vasc Health Risk Manag Volunme 403-415.
Luft, F. C. (2004) Hypertensive nephrosclerosis: update Curr Opin Nephrol Hypertens Volunme (2): 147-154.
Cooray, S. D., Edmonds, S. M., Tong, S., Samarasekera, S. P. and Whitehead, C. L. (2011) Characterization of symptoms immediately preceding eclampsia Obstetrics & Gynecology Volunme 995 – 999.
Gustavo, V., Luis R, H., Jocelyn Leon, P., Moraima, L. and Pedro, A. (2016) Differences in clinical presentation and pregnancy outcomes in antepartum preeclampsia and newonset postpartum preeclampsia: Are these the same disorder? Obstet Gynecol Sci Volunme (6): 434-443.
Zehra, K., Mertihan, K., Glucin, A. and Tekin, Y. (2011) Retinal Findings in Cases of Preeclampsia Perinatal Journal Volunme (2): 60-63.
Erdem, D., Mustafa, V., Ozer, D., Fatma Merve, B., Ayse Ayca, S., Y., A., Ufuk, A., Ozlem, Y. and Mehmet Atila, A. (2017) Evaluation of fundus findings in preeclampsia Medicine Science International Medical Journal Volunme (3): 406-409.
Lewinsky, R. M. and Riskin-Mashiah, S. (1998) Autonomic imbalance in preeclampsia: evidence for increased sympathetic tone in response to the supine-pressor test Obstet Gynecol Volunme (6): 935-939.