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Syncope and Related Diseases in Chronic Constitutional Hypotension: Gender Based Retrospective Observational Study in Symptomatic Women
Current Issue
Volume 5, 2017
Issue 3 (June)
Pages: 17-20   |   Vol. 5, No. 3, June 2017   |   Follow on         
Paper in PDF Downloads: 17   Since Aug. 1, 2017 Views: 920   Since Aug. 1, 2017
Authors
[1]
Alfonso Lagi, Internal Medicine Unit Villa Donatello Hospital, Firenze, Italy.
[2]
Simone Cencetti, Ospedale Santa Maria Nuova Syncope Unit, Firenze, Italy.
Abstract
Introduction: the association between chronic constitutional hypotension (CCH) and symptoms is uncertain both as pathophysiological correlation as a statistical link. The study was undertaken in order to investigate the existence of a significant association between CCH and symptoms and identify the most represented ones. Methods: females only have been used because of the higher incidence of CCH in their sex. The symptoms considered were studied in three groups of subjects: A and B groups, identified for systolic arterial pressure (SAP) <100 mmHg and diastolic blood pressure (DAP) <60 mmH, and finally a C group of control consisting of normotensive women. Symptoms considered were: dizziness, anxiety / or depression, asthenia and / or fatigue, transient loss of consciousness (TLC), accidental falls, and body mass index (BMI). Results: patients with CCH had significant incidence of anxiety / depression and asthenia / fatigue and TLC versus controls. Individuals with PAD <60 mmHg (group B) had a significance statistical difference of events also vs. the group A. Discussion and conclusion: the females with CCH are symptomatic and have a lower BMI than controls. The low value of PAD defines a major risk group for TLC and a worse prognosis.
Keywords
Syncope, Chronic Hypotension, Hypotension, Chronic Constitutional Hypotension, Transient Loss of Consciousness
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