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Hypertensive Heart Failure in Kumasi, Ghana
Current Issue
Volume 2, 2014
Issue 1 (February)
Pages: 39-43   |   Vol. 2, No. 1, February 2014   |   Follow on         
Paper in PDF Downloads: 39   Since Aug. 28, 2015 Views: 2174   Since Aug. 28, 2015
Isaac Kofi Owusu , Department of Medicine, College of Health Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana; Department of Medicine, Komfo Anokye Teaching Hospital, Kumasi, Ghana.
Yaw Adu-Boakye , Department of Medicine, Komfo Anokye Teaching Hospital, Kumasi, Ghana.
Lambert Appiah Tetteh , Department of Medicine, Komfo Anokye Teaching Hospital, Kumasi, Ghana.
Hypertension has become a major public health issue worldwide, and it has been found to be the most common cause of heart failure in many parts of sub-Saharan Africa. This was an observational study designed to determine the demographic and clinical characteristics of hypertensive heart failure patients seen at the department of medicine, Komfo Anokye Teaching Hospital (KATH), Kumasi, Ghana. Medical records of 180 hypertensive heart failure patients were selected using simple random sampling. The baseline demographic, clinical, chest X-ray, electrocardiographic (ECG) and echocardiographic characteristics of the patients were examined. One hundred and eighty (180) hypertensive heart failure were studied. They were aged between 24 - 88 years with the mean age ( SD) of 63.59 (±18.12) years. There were more females (52.22%; n=94) than males (47.78%; n=86). The mean systolic blood pressure ( SD) and the mean diastolic blood pressure ( SD) were 162.42 (± 32.18) and 92.29 (±18.54) respectively. The pulse rate ranged between 43-168 beats/minute with the mean pulse rate ( SD) of 85.24 (± 20.71) beats/minute. Most (46 %) of the patients presented with NYHA functional class 4. The most common presenting complaint was shortness of breath (72.22%), followed by easy fatiguability (50%), and palpitation (43.89%). The main clinical signs were pulmonary oedema (80%) and displaced apex beat (67.78%). Chest X-ray showed cardiomegaly in 71.11% of the patients. ECG LVH and echocardiographic LVH were seen in 75.56 % and 83.33% of the patients respectively. Prevalence of heart failure with preserve ejection fraction (HFPEF) was 62.22 %. Left ventricular systolic dysfunction with or with diastolic dysfunction was seen in 37.78 % of the patients. In conclusion, the most common clinical presentation of patients seen at KATH, Kumasi, with hypertensive heart failure were shortness of breath, easy fatiguability, pulmonary oedema and displaced apex beat. The prevalence of heart failure with preserved ejection fraction (HFPEF) among the patients was high.
Hypertension, Heart Failure, Prevalence, Left Ventricular Hypertrophy, Ghana
Opie LH, Seedat YK. Hypertension in sub-Saharan African populations. Circulation. 2005;112:3562–3568.
Kengne AP, Awah PK, Fezeu L, Mbanya JC. The burden of high blood pressure and related risk factors in urban sub-Saharan Africa. Evidence from Douala in Cameroon. Afr Health Sci. 2007;7:38–44.
Plange-Rhule J, Philips R, Acheampong JW, Sagar-Malik AK, Cappuccio FP, Eastwood JB. Hypertension and renal failure in Kumasi, Ghana. J Hum Hyp 1999; 13: 37-40.
Falase AO, Ayeni O, Sekoni GA, Odia OJ. Heart failure in Nigerian hypertensives. Afr J Med Sci 1983; 12: 7-15.
Van der Sande MA. Cardiovascular disease in sub-Saharan Africa: a disaster waiting to happen. Neth J Med. 2003;61:32–36.)
Owusu IK. Causes Of Heart Failure As Seen In Kumasi, Ghana: The Internet Journal of Third World Medicine. 2007; Volume 5, Number 1.
Amoah AG, Kallen C. Aetiology of heart failure as seen from a National Cardiac Referral Centre in Africa. Cardiology 2000; 93 (1-2): 11-18.
Owusu IK, Boakye YA (2013) Prevalence and Aetiology of Heart Failure in Patients Seen at a Teaching Hospital in Ghana. J Cardiovasc Dis Diagn 1: 131. doi:10.4172/2329-9517.1000131
Mendez GF, Cowie MR (2001) The epidemiological features of heart failure in developing countries: a review of the literature. Int J Cardiol 80: 213-219.
Damasceno A, Cotter G, Dzudie A, Sliwa K, Mayosi BM. Heart failure in sub-saharan Africa: time for action. J Am Coll Cardiol 2007; 50(17): 688-93.
Toure LA, Salissou O, Chapko MK. Hospitalisations in Niger (West Africa) forcomplications from arterial hypertension. Am J Hypertens 1992, 5: 322-324.
Cooper RS, Amoah AG, Mensah GA. High blood pressure: the foundationfor epidemic cardiovascular disease in African populations. Ethn Dis. 2003; 13 (2 Suppl 2): S48-S52.
Isezuo AS, Omotoso ABO, Gaye A, et al. One year survival among sub-Saharan Africans with hypertensive heart failure. Tropical Cardiology 2000; 26/no 103: 57-60.
Kizer, JR, Arnett, DK, Bella, JN, et al. Differences in left ventricular structure between black and white hypertensive adults: the Hypertension Genetic Epidemiology Network study. Hypertension 2004; 43:1182.
Van Hoeven, KH, Factor, SM. A comparison of the pathologic spectrum of hypertensive, diabetic and hypertensive-diabetic heart disease. Circulation 1990; 82:848.
Dzau, VJ. Tissue renin-angiotensin system in myocardial hypertrophy and failure. Arch Intern Med 1993; 153:937.
Araoye MA, Olowoyeye O. The clinical spectrum of hypertensive heart failure: a point score system for solving an old problem. East Afr. Med J. 1984; 61:306-315.
McKee PA, Castelli WP, McNamara PM, Kannel WB (1971) The natural history of congestive heart failure: the Framingham study. N Engl J Med 285: 1441-1446.
Chobanian AV, Bakris GL, Black HR, Cushman WC, Green LA, et al. (2003) The seventh report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure: the JNC 7 report. JAMA 289: 2560-2571.
Lemogoum D, Seedat YK, Mabadeje AF, Mendis S, Bovet P, et al. (2003) Recommendations for prevention, diagnosis and management of hypertension and cardiovascular risk factors in sub-Saharan Africa. J Hypertens 21: 1993-2000.
Scott R. C. The electrocardiographic diagnosis of left ventricular hypertrophy. Am Heart J. 1960; 59:155.
Owusu IK. Treatment Of Heart Failure In A Teaching Hospital In Ghana, West Africa. The Internet Journal of Third World Medicine. 2007 Volume 4 Number 2.
Isezuo AS, Omotoso AB, Araoye MA, Carr J, Corrah T. Determinants of prognosis among black Africans with hypertensive heart failure. Afr J Med Sci. 2003 Jun; 32 (2): 143-149.
Oyoo GO, Ogola EN. Clinical and socio demographic aspects of congestive heart failure patients at Kenyatta National Hospital, Nairobi. East Afr Med J. 1999 Jan; 76 (1): 23-27.
Owusu IK. Electrocardiographic Left Ventricular Hypertrophy In Patients Seen With Hypertensive Heart Failure . The Internet Journal of Third World Medicine. 2007 Volume 6 Number 1.
Task Force report. Guidelines for the diagnosis and treatment of chronic heart failure, European Society of Cardiology. Eur Heart J (2001) 22, 1527-1560.
Ho KKL, Pinsky JL, Kannel WB, Lery D. The epidemiology of heart failure: The Framingham study. J Am Coll Cardiol 1993; 22 (Supplement A): 6A - 13A.
Kolo PM, Jibril YB, Sanya EO, et al. Hypertension-Related Admissions and Outcome in a Tertiary Hospital in Northern Nigeria. International Journal or Hypertension volume 2012.
Psaty BM, Furberg CD, Kuller LH, et al. Association between blood pressure level and the risk of myocardial infarction, stroke and total mortality: The Cardiovascular Health Study. Arch Intern Med 2001; 161:1183-1192.
Ike SO, Onwubere BJ. The relationship between diastolic dysfunction and the level of blood pressure in Blacks. Ethn Dis. 2003; 13(4): 463 - 469.
Oyati IA, Danbauchi SS, Alhassan MA, Isa MS. Diastolic Dysfunction in Persons with Hypertensive Heart Failure. Journal of the National Medical Association, 2004; Vol. 96, No. 7.
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