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2015 Persian Gulf Criteria for Early Diagnosis of Polymyositis/Dermatomyositis
Current Issue
Volume 3, 2015
Issue 5 (October)
Pages: 169-172   |   Vol. 3, No. 5, October 2015   |   Follow on         
Paper in PDF Downloads: 31   Since Sep. 7, 2015 Views: 1755   Since Sep. 7, 2015
Iraj Salehi-Abari, Rheumatology Research Center, Amir Alam Hospital, Tehran University of Medical Sciences, Tehran, Iran.
The idiopathic inflammatory myopathies are a group of chronic inflammatory diseases with unknown etiology involving muscle resulting myositis. It may be an autoimmune process and multiple autoantibodies have been detected in this group of disorders. Polymyositis (PM) is a member of this group in which Myositis is the predominant feature of a systemic disease involving muscle (Myositis), heart (Myocarditis, conduction abnormalities, arrhythmia and coronary heart disease), lung (Interstitial lung disease), Gastrointestinal (dysphagia, nasal regurgitation and/or aspiration), joints (arthralgia/arthritis) and so on. Myositis as the cardinal involvement in PM is presented as symmetric proximal muscle weakness. climbing stairs and getting up with difficulty are the history of these patients. Muscle enzymes including Creatine Kinase (CK), Lactate Dehydrogenase (LDH), aldolase, aspartate aminotransferase (AST) and alanine aminotransferase (ALT) can be increased in patients with myositis. In Dermatomyositis, skin involvement is a major finding along with other manifestations as same as all the features can be seen in PM. As same as other systemic inflammatory Rheumatic diseases the diagnosis of PM/DM can be established by clinical/laboratory judgment of an expert rheumatologist. Bohan and Peter classification criteria for PM/DM has been used since 1975. We know that, Bohan and Peter criteria cannot exactly differentiate the polymyositis from muscular dystrophies and many other myopathies and after that, the discovery of MSA and detection of the role of MRI in diagnosis of muscle inflammation have been introduced. In this letter, the corresponding author wants to deliver a new diagnostic criteria for early detection of PM/DM along with a guideline for approaching to diagnosis of PM/DM.
Polymyositis, Dermatomyositis, Bohan and Peter Criteria, Persian Gulf Criteria
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