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Detection of Abnormalities for Diagnosing of Children with Asperger Disorder Using of Quantitative Electroencephalography Analysis
Current Issue
Volume 3, 2015
Issue 1 (February)
Pages: 14-20   |   Vol. 3, No. 1, February 2015   |   Follow on         
Paper in PDF Downloads: 14   Since Aug. 28, 2015 Views: 976   Since Aug. 28, 2015
Mohammad Reza Mohammadi, Child and Adolescent Psychiatry, Psychiatry and Psychology Research Centre (PPRC), Tehran University of Medical Science, Tehran, Iran.
Ali Sheikhani, Department of Biomedical Engineering, Islamic Azad University, Science and Research Branch, Tehran, Iran.
Hamid Behnam, Electrical Engineering Department, Iran University of Science & Technology, Tehran, Iran.
Maryam Noroozian, Neurology, Psychiatry and Psychology Research Centre (PPRC), Roozbeh Hospital, Tehran University of Medical Science, Tehran, Iran.
Mohammad Mohammadi, Iranian Behavioural and Psychological Centre for Children and Adolescents, Tehran, Iran.
Asperger disorder, one of the autistic spectrum disorders, is characterized by impairments in reciprocal social interaction and communication. In this study, spectrogram and coherence values with statistical analysis are used for evaluating quantitative electroencephalography (qEEG).Seventeen children with Asperger disorder (aged between 6 to 11)and thirteen control children (same age) were examined. It is shown that gamma frequency band (34-44Hz) could be used to separate the two groups very well (96.7%) in relaxed eye-opened condition. The children with Asperger disorder showed significant lower spectrogram criteria value (p<0.01) at Fp1 electrode and (p<0.05) at Fp2 and T6. Coherence values at 112 pairs of EEG neighbor electrodes indicated that the connectivity at electrode pairs (T4, P4), (T4, Cz), (T4, C4) and (T4, O1) had significant differences (p<0.01). More abnormalities were related to the connectivity of right temporal lobe with the other lobes. The results demonstrate that analysis of qEEG is useful for diagnosis of children with Asperger disorder using spectrogram and coherence values.
Asperger and Autism Disorders, Quantitative Electroencephalography, Spectrogram and Coherence Values
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