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About a General Approach of Primary Lung Lymphomas
Current Issue
Volume 1, 2013
Issue 1 (December)
Pages: 5-16   |   Vol. 1, No. 1, December 2013   |   Follow on         
Paper in PDF Downloads: 12   Since Aug. 28, 2015 Views: 2034   Since Aug. 28, 2015
Authors
[1]
Mona Mlika, Department of Pathology, Abderrahman Mami Hospital Faculté de médecine de Tunis, Université Tunis El Manar.
[2]
F Mezni, Department of Pathology, Abderrahman Mami Hospital Faculté de médecine de Tunis, Université Tunis El Manar.
Abstract
Primary pulmonary lymphomas are very rare accounting for 0.5 to 1% of the primary malignant tumors of the lung. They are dominated by the mucosa-associated-lymphoid tissue lymphoma, high grade B cell lymphoma and lymphomatoid granulomatosis. The diagnosis and the management of these tumors remain debated and challenging. We target to assess the pathogenesis, clinical, microscopic and radiologic characteristics of these tumors. In the other hand, we target to highlight the main treatment modalities and to emphasize on the necessity of a standardization of the management of these tumors.
Keywords
MALT Lymphoma, High Grade B Cell Lymphoma, Lymphomatoid Granulomatosis, Primary Lung Lymphoma
Reference
[1]
Cadranel J, Wislez M, Antoine M. Primary Pulmonary Lymphoma. Eur Respir J 2002;
[2]
20: 750.762.
[3]
Isaacson PG, Norton AG. Extra nodal lymphomas. Churchill Livingstone, New York
[4]
1994.
[5]
Freeman C, Berg JW, Cutler SJ. Occurrence and prognosis of extranodal lymphomas. Cancer 1972; 29: 252.60.
[6]
The Non.Hodgkin Pathologic Classification Project. National cancer institute sponsored study of classification of non Hodgkin’s lymphoma, summary and description of working formulation for clinical usage. Cancer 1982 ; 49 : 2112.35
[7]
Saltzstein SL. Pulmonary malignant lymphomas and pseudolymphomas: classification, therapy, and prognosis. Cancer 1963; 16: 928.955.
[8]
Koss MN, Hochholzer L, Nichols PW, Wehunt CWD, Lazarus AA. Primary non Hodgkin lymphoma and pseudo lymphoma of lung: a study of 161 patients. Hum Pathol 1985; 14: 1024.38.
[9]
L’hoste R, Filippa D, Lieberman P, Bretsky S. Primary pulmonary lymphoma a clinicopathogic analysis of 36 cases. Cancer 1984; 54: 1397.406.
[10]
Nicholson AG, Wotherspoon AC, Diss TC et al. Pulmonary B.cell Non.Hodgkin’s lymphomas. The value of immunohistochemistry and gene analysis in diagnosis. Histopathology 1995; 26: 395.403.
[11]
Isaacson PG, Wright DH. Malignant lymphoma of mucosa associated lymphoid tissue. A distinctive type of B cell lymphoma. Cancer 1983; 52: 1410.16.
[12]
Jaffee S, Harris NL, Stein H, Vardiman J W. Tumours of Hematopoietic and Lymphoid Tissues. World Health Organisation Classification of Tumours 2001.
[13]
Isaacson PG, Spincer J. Malignant lymphoma of mucosa.associated lymphoid tissue. Histopathol 1987; 7: 445.62.
[14]
Liebow AA, Carrington CR, Friedman PG. Lymphomatoid granulomatosis. Hum Pathol 1972; 3: 475.558.
[15]
Liebow AA. The J Burns Ambrson Lecture. pulmonary angiitis and granulomatosis. Am Rev Respir Dis 1973; 108: 1.18.
[16]
Lipford EH Jr, Margolick JB, Longo DL, Fauci AS, Jaffe ES. Angiocentric immunoproliférative lesions: a clinicopathologic spectrum of post thymic T.cell proproliferations. Blood 1988; 72: 1674.1681.
[17]
Mederios LJ, Peiper SC, Elwood L, Yano T, Raffeld M, Jaffe ES. Angiocentric immunoproliferative lesions: a molecular analysis of eight cases. Hum Pathol 1991;22: 1150.1157.
[18]
Myers JL, Kurtin PJ, Katzenstein AL et al. Lymphomatoid granulomatosis. Evidence of immunophenotypic diversity band relationship to Epstein . Barr virus infection. Am J Surg Pathol 1995; 19:1300.12.
[19]
Li G, Hansmann M, Zwingers TR, Lennert K: Primary lymphomas of the lung: morphological, immunohistochemical and clinical features. Histopathol 1990; 16: 519.31.
[20]
Wislez M, Antoine M, Bellocq A, Carette MF, Cadranel J. Lymphome pulmonaire de type MALT : mise au point. Rev Pneumol Clin 2007 ;63 : 177.82.
[21]
Richmond I, Pritchard GE, Ashcroft T et al. Bronchus associated lymphoid tissue (BALT) in human lung: its distribution in smokers and non smokers. Thorax 1993; 48:1130.4.
[22]
Strimlan C, Rosenow E, Divertie M, Eg H. Pulmonary manifestations of Sjögren’s syndrome. Chest 1979; 70: 354.61.
[23]
Graham BB, Mathisien DJ, Eugene JM, Takvorien RW. Primary pulmonary lymphoma. Ann thorac surg 2005; 80: 1248.53.
[24]
Basot M, Cadranel J, Benayoun S et al. Primary pulmonary AIDS.related lymphoma: radiographic and CT findings. Chest 1999 ; 116 :1282.1286.
[25]
Rosenwald A, Ott G, Stilgenbauer S, Kalla J, Bredt M, Katzenberger T et al. Exclusive detection of the t(11;18)(q21;q21) in extranodal marginal zone B cell lymphomas (MZBL) of MALT type in contrast to other MZBL and extranodal large B cell lymphomas. Am J Pathol. 1999; 155: 1817–1821.
[26]
Remstein ED, Kurtin PJ, James CD, Wang XY, Meyer RG, Dewald GW. Mucosaassociated lymphoid tissue lymphomas with t (11; 18) (q21; q21) and mucosaassociated lymphoid tissue lymphomas with aneuploidy develop along different pathogenetic pathways. Am J Pathol 2002; 161: 63–71.
[27]
Streubel B, Lamprecht A, Dierlamm J, Cerroni L, Stolte M, Ott G et al. t(14;18)(q32;q21) involving IGH and MALT1 is a frequent chromosomal aberration in MALT lymphoma. Blood 2003; 101: 2335–2339.
[28]
Guinee JE, Kigma D. Pulmonary lymphomatoid granulomatosis. Evidence for a prolifération of Epstein . Barr virus infected b.lymphocytes with preminent T.cell component and vasculitis. Am J Surg Pathol 1994; 18: 753.764.
[29]
Kennedy JL, Nathwany BN, Burke JS, Hill LR, Rappaport H. Pulmonary lymphomas and other pulmonary lymphoid lesions. A clinicopathologic and immunologic study of 64 patients. Cancer 1985; 56: 539.552.
[30]
Katzenstein AL, Liebow AA. Lymphomatoid granulomatosis. A clinicopathologic study of 152 cases. Cancer 1979; 43: 360.373.
[31]
Le Tourneau A, Auduin J, Garbe L et al. Primary pulmonary malignant lymphoma, clinical and pathological findings, immunocytochemical and ultrastructural studies in 15 cases. Hematol Oncol 1984; 1: 49.60.
[32]
Cordier JF, Chailleux E, Lauque D et al. Primay pulmonary lymphomas. A clinical study of 70 cases in non immune.compromised patients. Chest 1993; 103: 201.208.
[33]
Ferraro P, Trastek Vf, Adlakha H, Deschamps C, Allen Ms, Pairolero Pc. Primary non Hodgkin’s lymphoma of the lung. Ann thorac Surg 2000; 69:993.7.
[34]
Ferraro P, Trastek Vf, Adlakha H, Deschamps C, Allen Ms, Pairolero Pc. Primary non hodgkin’s lymphoma of the lung. Ann thorac Surg 2000; 69:993.7.
[35]
Kurtin PJ, Myers JL, Adlahka H, Strikler JG, Lohse C, Pankratz S et al. Pathologic and clinical features of primary extra nodal marginal zone B.cell lymphoma of MALT type. Am J Surg Pathol 2001; 25: 997.1008.
[36]
Kim JH, Lee SH, Park J, Kim HY, Lee SI, Park JO et al. Primary pulmonary nonhodgkin’s lymphoma. JPN J Clin Oncol 2004; 34 : 510.4.
[37]
Ooi GC, Chim CS, Lie AK, Tsang KW. Computed tomography features of primary pulmonary non hodgkin’s lymphoma. Clin Radiol 1999; 54: 438.43.
[38]
Dee PM, Arora NS, Innes DJ. The pulmonary manifestations of lymphomatoid granulomatosis. Radiology 1982; 143:613.18.
[39]
Kyung S, Yookyung K, Primack L. Imaging of pulmonary lymphomas. AJR 1997 ;168 : 339.345.
[40]
Kaba S. Cytopathology 2011 ;22 :346.351
[41]
Drent M, Wagenaar SS, Mulder PH, Van Den Bosch JM. Bronchoalveolar lavage fluid profiles in sarcoidosis, tuberculosis and non hodgkin’s ans hodgkin’s disease. An evaluation of differences. Chest 1994; 105: 514.19.
[42]
Zompi S, Coudrec LI, Cadranel J et all. Clonality analysis of alveolar B lymphocytes contributes to the diagnostic strategy in clinical suspicion of pulmonary lymphoma. Blood 2004; 103: 3208.15.
[43]
Zompi S, Coudrec LI, Cadranel J et all. Clonality analysis of alveolar B lymphocytes contributes to the diagnostic strategy in clinical suspicion of pulmonary lymphoma.
[44]
Blood 2004; 103: 3208.15.
[45]
Cordier JF, Chailleux E, Lauque D et al. Primay pulmonary lymphomas. A clincal study of 70 cases in nonimmunocompromised patients. Chest 1993; 103: 201.208.
[46]
Kurtin PJ, Myers JL, Adlahka H, Strikler JG, Lohse C, Pankratz S et al. Pathologic and clinical features of primary extra nodal marginal zone B.cell lymphoma of MALT type. Am J Surg Pathol 2001; 25: 997.1008.
[47]
Terada T. CD5.positive marginal zone B.cell lymphoma of the mucosa.aasociated lymphoid tissue (MALT) of the lung. Diag Pathol 2012;7:16
[48]
Strollo DC, Rosado.De.Christenson ML, Jett JR. Primary mediastinal tumors: part II. Tumors of the middle and posterior mediastinum Chest 1997; 112: 1344.57.
[49]
Hollister Jr D, Lee MS, Eisen RN, Fey C. Sarcoidosis Mimicking progressive Lymphoma. J Clin Oncol.2005 ; 23 : 31.35.
[50]
Jung CY, Kwon KY. A case of cynchronous lung adenocarcinoma and extranodal marginal zone B.cell lymphoma of mucosa.associated lymphoid tissue type. Tuberc respire 2012;73:61.66
[51]
Travis WD, Galvin JR. Non.neoplastic pulmonary lesions. Thorax 2001; 56: 964.71.
[52]
Bienenstock J, Johnston N, Perry D. Bronchial lymphoid tissue. Lab Invest 1973; 28: 686.98.
[53]
Kradin RL, Mark EJ. Benign lymphoid disorders of the lung, with a theory regarding their development. Hum Pathol 1983; 14: 857.67.
[54]
Lipford EH Jr, Margolick JB, Longo DL, Fauci AS, Jaffe ES. Angiocentric immunoproliferative lesions: a clinicopathologic spectrum of post thymic T.cell proproliferations. Blood 1988; 72: 1674.1681.
[55]
Zanzani PL, Pellegrini C, Gandolfi L, et al. Extranodal marginal zone B.cell lymphoma of the lung : experience with fludarabine and mitoxantrone.containing regimens. Hematol Oncol 2012. DOI: 10.1002/hon.2039.
[56]
Fauci AS, Harley JB, Robrts WC et al. NIH conference. The idiopatic hypereosinophilic syndrome. Clinical, pathophysiologic, and therapeutic considerations. Ann Intern Med 1982; 97: 78.92.
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