Comparative Haemorrheological Changes in Third Trimester of Pregnancy and in the First Stage of Labour
Physiological modification of blood during pregnancy has been well documented. In the same vein, stressors have been implicated in blood profile changes. This study therefore investigates the haemorrheological changes in normal pregnancy and during the first stage of labour; since labour is a highly stressful physiological event. This study was conducted in Benin City, Nigeria and it involves 10 normal pregnant women in their 3rd trimester (control) and 10 parturient in their first stage of labour (test). Blood sample was collected from each subject and analysed using Swelab Alfa Automated Haematology Analyzer. The results showed that except for MCHC, pregnant women in their third trimester of pregnancy (as control) have a non significant higher RBC, MCV, RDWa, RDW, Hct, HGB and MCH than parturients women in their first stage of labour. On the other hand, parturients women in their first stage of labour have significantly higher (p<0.05) mean relative plasma viscosity and fibrinogen concentration than pregnant women in their third trimester of pregnancy (as control). Based on the findings of this study, stress induced by first stage of labour may has significant effect on relative plasma viscosity and fibrinogen concentration. By implication, parturient should be optimized in terms of hydration and normoglycemia during the first stage of labour.
Labour, Pregnancy, Haemorrheology, Benin City, Nigeria
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