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Phytochemical Screening and Mineral Potentials of the Kernel of Dacryodes klaineana (Pierre) H.J.Lam
Current Issue
Volume 4, 2019
Issue 1 (January)
Pages: 7-12   |   Vol. 4, No. 1, January 2019   |   Follow on         
Paper in PDF Downloads: 14   Since Apr. 26, 2019 Views: 976   Since Apr. 26, 2019
Authors
[1]
Akhideno Lawson Oseigbokhan, Moist Forest Zonal Research Station, Forestry Research Institute of Nigeria, Edo State, Nigeria.
[2]
Rafiu Basirat Olabisi, Biomedcinal Research Center, Forestry Research Institute of Nigeria, Ibadan, Nigeria.
[3]
Lawal Ibraheem Oduola, Biomedcinal Research Center, Forestry Research Institute of Nigeria, Ibadan, Nigeria.
[4]
Ogboru Rachel Ogheneovo, Research Coordinating Unit, Forestry Research Institute of Nigeria, Ibadan, Nigeria.
Abstract
The importance of plant to human life is imperious, ranging from being used as food as well as shelter. There is a correlation between traditional uses of a plant and its activity in biological screening system. Dacryodes klaineana (DK) is a woody evergreen perennial with edible fruits in the family Buseraseae, which are widely applied in traditional folk medicine to treat painful menstruation, enema, cough and skin diseases. The aim of this is study was to determine the chemical and elemental composition of DK that are responsible for its activities as previously mentioned in its folkloric uses. Phytochemical screening and Mineral element composition of Dacryodes klaineana kernel was carried out using standard methods. Phytochemical screening result investigated showed that the kernel possessed some secondary metabolites which include tannins, flavonoids, alkaloids and cardiac glycosides. Despite saponins, free and combined anthraquinone being absent the presence of these secondary metabolites give credence to the fact that the seed kernel possess medicinal properties. Results obtained in the mineral analysis indicated the presence of some micro and macro nutrients such as Potassium (K), Calcium (Ca), Iron (Fe), Zinc (Zn) among others, are within the acceptable health range. The health benefits of these elements and phytochemicals cannot be ruled out, which makes DK an excellent source of minerals and secondary metabolites that should be embraced by nutraceutical and pharmaceutical industries.
Keywords
Phytochemical Screening, Mineral Analysis, Dacryodes klaineana, Kernel, Sodium, Potassium, Zinc, Health Benefit
Reference
[1]
Moshi, M. J., Otieno, D. F., Weisheit, A., 2012. Ethnomedicine of the Kagera Region, north western Tanzania. Part 3: plants used in traditional medicine in Kikuku village, Muleba District. Journal of Ethnobiology and Ethnomedicine, Vol. 8 (1): Page 1.
[2]
Anushia, C., Sampathkumar, P. and Ramkumar, L., 2009. Antibacterial and Antioxidant Activities in Cassia auriculata. Global Journal of Pharmacology, Vol. 3 (3): 127-130.
[3]
Soares, J. M., Sampaio, A., Ferreira, L. M., Santos, N. C., Marques, P., Marques, F., Palha, J. A., Cerqueira, J. J., Sousa, N., 2013. Stress Impact on Resting State Brain Networks. Ed: Wang Zhan, University of Maryland, College Park, United States of America. Plos One, Vol. 8 (6): e66500.
[4]
Saxena AK, Panhotra BR, Naguib M, Nabil AM, Sundaram DS, Venkateshappa CK, et al. 2001. Prevalence of hepatitis C antibodies among hemodialysis patients in Al-Hasa region of Saudi Arabia. Saudi Journal of Kidney Diseases and Transplantation, Vol. 12: 562-5.
[5]
Neuwinger, H. D., 2000. African traditional medicine: A dictionary of plant use and applications, p. 589, Medpharm Scientific Publishers, Stuttgart, Germany.
[6]
PROTA, 2008. Medicinalplants. Plant resources of tropical Africa, ed. by G. H. Schmelzer & A. Gurib-Fakim. Wageningen, PROTA Foundation - Backhuys - CTA. Vol. 11 (1): 869.
[7]
Kryn, J. M. and Fobes, E. W. 1959. The woods of Liberia. Forest Products Laboratory Publication 2159, USDA-Forest Service, Madison, WS. Pp 49–51.
[8]
Burkill, H. M., 1985, ‘The useful plants of west tropical Africa’, 2nd Edition. Volume 1, Families A–D. Royal Botanic Gardens, Kew, Richmond, United Kingdom Pp, 960.
[9]
Keay, R. W. J., Onochie, C. F. A., &Stanfield, D. P., 1964. Nigerian Trees. Volumes one-four. Federal Department of Forest Research, Ibadan, Nigeria, Vol. 7: 255-6.
[10]
Vivien, J. & Faure, J. J., 1996. Fruitiers sauvages d’Afrique: especes du Cameroun Paris. Ministere de la cooperation, Wageningen: Centre technique de cooperation agricole et rurale. Clohars carnet (Frauce): Ed. Nguila-Kerou, Pg: 416.
[11]
Brink, M., 2008. Dacryodeskalineana (Pierre) H. J. In: Louppe, D., Oteng-Amoako, A. A.; Brink, M. (Editors). PROTA (Plant Resources of Tropical Africa/Resources végétales de l’Afrique tropicale), Wageningen, Netherlands.
[12]
Sofowora, A. 2008. Medicinal Plants and traditional medicine in Africa, 3rd Ed; Spectrum Books Ltd, Ibadan, Nigeria, Pg: 439.
[13]
Harborne, J. B. 1998. Phytochemical methods. 3rd ed., Chapman & Hall, London. Pg: 5-30.
[14]
A. O. A. C. (1990). Association of Official Analytical Chemist. Official Methods of Analysis of the AOAC. 15TH Edition, Washington, D. C.
[15]
Trease, G. C. and Evans W. C. 1989. Trease& Evan’s textbook of pharmacognosy. 13th Edn, Cambridge University press, London 546.
[16]
Nwokonkwo, D. C., 2014. The Phytochemical study and antibacterial activities of the seed extract of Dacryodes edulis (African Native Pear). American Journal of Scientific and Industrial Research, Vol. 5 (1): 7-12.
[17]
Ajibesin, K. K., 2011. Dacryodes edulis (G. Don) H. J. Lam: A review on its medicinal, phytochemical and economical properties. Research Journal of MedicinalPlant, Vol. 5: 32-41.
[18]
Havsteen, B. H., 2002. The biochemistry and medical significance of the flavonoids. Pharmacology & Therapeutics, Vol. 96 (2-3): 67-202.
[19]
Walker, A. R. and Silans, R., 1961. Les plantes utiles du Gabon. Paul Lechevailer, Paris. Pg: 19-132.
[20]
Igoli, J. O., Ogaji, O. G, Tor- Anyiin, T. A., and Igoli, N. P., 2005. Traditional medical practices among the Igede people of Nigeria. Part II. African Journal of Biotechnology, Vol. 6: 950 -952.
[21]
Ekpa, O., 1993. The use of Raphia hookeri and Pachylobus edulis in cosmetic formulation. Discovery Innovation, Vol. 5: 313 -316.
[22]
Havard health letter, 2009. Potassium and sodium out of balance. Harvard health publishing, Harvard medical school, published.
[23]
Institute of Medicine, 2005. Dietary reference intakes for water, potassium, sodium, chloride and sulphate. Washington, DC.
[24]
Viera, A. J. and Wouk, N., 2015. Potassium disorders: Hypokalemia and Hyperkalemia. American Family Physician, Vol. 92: 487 -95.
[25]
Stone, M. S., Martyn, L. and Weaver, C. M., 2016. Potassium intake, bioavailability, hypertension and glucose control. Nutrients, Vol. 8.
[26]
Preuss H. G. and Clouatre, D. L., 2012. Sodium, chloride and potassium. In: Erdman, J. W., Macdonald, I. A. and Zeisel, S. H., eds. Present knowledge in Nutrition. 10th ed. Washington, DC: Willey-Blackwell; Vol. 475-92.
[27]
Weaver, C. M., 2013. Potassium and health. Advances in Nutrition, Vol. 4: 368S-377S.
[28]
MedlinePlus, 2015. Definitions of health terms: Minerals. U. S. National library of medicine, MD 20894.
[29]
Yang, Q., Liu, T., Kuklina, E. V., Flanders, W. D., Hong, Y., Gillespie, C., Chang, M. H., Gwinn, M., Dowling, N., Khoury, M. J., and Hu, F. B., 2011. Sodium, potassium intake and mortality among US adults: prospective data from the Third National Health and Nutrition Examination Survey. Archives of Internal Medicine, Vol. 171 (13): 1183-91.
[30]
World Cancer Research Fund, 2007. Food, nutrition, physical activity and the prevention of cancer: A global perspective. American Institute for Cancer Research, London.
[31]
Devine, A., Criddle, R. A, Dick, I. M., Kerr, D. A., Prince, R. L., 1995. A longitudinal study of the effect of sodium and calcium intakes on regional bone density in postmenopausal women. American Journal of Clinical Nutrition, Vol. 62: 740-5.
[32]
Clarkson, P. and Haymes, E., 1995. Exercise and mineral status of athletes: Calcium, magnesium, phosphorus and iron. Department of General Chemistry Poznañ University of Medical Sciences DDS Program. Medicine & Science in Sports and Exercise, Vol. 27: 831-845.
[33]
Cranney A, Horsley T, O’Donnell S, Weiler HA, Puil L, Ooi DS, Atkinson SA, Ward LM, Moher D, Hanley DA, Fang M, Yazdi F, Garritty C, Sampson M, Barrowman N, Tsertsvadze A, Mamaladze V., 2007. Effectiveness and Safety of Vitamin D in Relation to Bone Health. Evidence Report/Technology Assessment No. 158 (Prepared by the University of Ottawa Evidence-based Practice Center (UO-EPC) under Contract No. 290-02-0021. AHRQ Publication No. 07-E013. Rockville, MD: Agency for Healthcare Research and Quality.
[34]
Bolland MJ, Leung W, Tai V, Bastin S, Gamble GD, Grey A, Reid IR., 2015. Calcium intake and risk of fracture: systematic review. British Medical Journal, Vol. 351: h4580.
[35]
Gao, X., LaValley, M. P., Tucker, K. L., 2005. Prospective studies of dairy product and calcium intakes and prostate cancer risk: a meta-analysis. Journal of the National Cancer Institute, Vol. 97: 1768-77.
[36]
Slattery M, Edwards S, Boucher K, Anderson K, Caan B. Lifestyle and colon cancer: an assessment of factors associated with risk. American Journal of Epidemiology, Vol. 150: 869-877.
[37]
Michaelsson, K., Melhus, H., Warensjo, L. E., Wold, A., Byberg, L., 2013. Long term calcium intake and rates of all cause and cardiovascular mortality: community based prospective longitudinal cohort study. British Medical Journal, Vol. 12 (346): f228.
[38]
Wang, L., Manson, J. E., Buring, J. E., Lee, I. M,, Sesso, H. D., 2008. Dietary intake of dairy products, calcium, and vitamin D and the risk of hypertension in middle-aged and older women. Hypertension, Vol. 51 (4): 1073- 1079.
[39]
Allender, P. S., Cutler, J. A., Follmann, D., Cappuccio, F. P., Pryer, J., Elliott, P., 1996. Dietary calcium and blood pressure. Annals of Internal Medicine, Vol. 124: 825 –831.
[40]
Curhan, G. C., Willett, W. C., Speizer, F. E., Spiegelman, D., Stampfer, M. J., 1997. Comparison of dietary calcium with supplemental calcium and other nutrients as factors affecting the risk for kidney stones in women. Annals of Internal Medicine, Vol. 126 (7): 497-504.
[41]
Cudihy, D., Lee, R. V., 2009. The pathophysiology of pre-eclampsia: current clinical concepts. Journal of Obstetrics and Gynaecology, Vol. 29: 576- 582.
[42]
Heaney, R. P., 2003. Normalizing calcium intake: projected population effects for body weight. Journal of Nutrition, Vol. 133: 268S-70S.
[43]
Hart, E. B. Steenbock, H., Waddell, J., 1928. Iron nutrition. VII: Copper is a supplement to iron for hemoglobin building in the rat. The Journal of Biological Chemistry, Vol. 77: 797–833.
[44]
Takeda, A., 2003. Manganese action in brain function. Brain research review, Vol. 41 (1): 79-87.
[45]
Crow, J. P., Calingasan, N. Y., Chen, J., Hill, J. L., Beal, M. F., 2005. Manganese porphyrin given at symptom onset markedly extends survival of ALS mice. Annals of Neurology, Vol. 58 (20): 258-65.
[46]
George, A. C., 2016. Copper and Human Health and Safety. International Copper Association Limited, 260 Madison Avenue, New York, NY 10016, USA.
[47]
Scheiber, I., Dringen, R., Mercer, J. F. B., 2013. Copper: Effects of Deficiency and Overload. In Sigel, Astrid; Sigel, Helmut; Sigel, Roland K. O. Interrelations between Essential Metal Ions and Human Diseases. Metal Ions in Life Sciences. Springer, Vol. 13: 359–87.
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