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Simple UV Spectrophotometric Method for the Analysis of Gemifloxacin
Current Issue
Volume 3, 2015
Issue 5 (October)
Pages: 63-66   |   Vol. 3, No. 5, October 2015   |   Follow on         
Paper in PDF Downloads: 66   Since Nov. 3, 2015 Views: 5155   Since Nov. 3, 2015
Authors
[1]
Safila Naveed, Faculty of Pharmacy, Jinnah University for Women, Karachi, Pakistan.
[2]
Sania Basheer, Faculty of Pharmacy, Jinnah University for Women, Karachi, Pakistan.
Abstract
Gemifloxacin (GFX) is a broad spectrum flouroquinolone antibiotic. It is extensively used for the treatment of respiratory and UTI infections. Aim of our study was to develop a simple, quick, economical but accurate method for the routine analysis of GFX. For that purpose distilled water was used as solvent, stock solution and dilutions were made using distilled water. For comparison studies of two different brands were taken for preparation of solution. Samples were prepared in the range of 100ppm to 6.25 ppm concentration. Their absorbance was taken in a 1cm quartz cell by spectrophotometer in the UV range of 200-400nm and maxima absorbance was measured at 294nm using water as a blank. Results were found by plotting linearity graph and calculating regression equations and it was found 0.999. Hence the proposed method can be employed for the routine analysis of GFX as it is simple, quick and efficient.
Keywords
Gemifloxacin, UV Spectrophotometer, Analysis
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Safila Naveed and Fatima Qamar (2014) UV spectrophotometric assay of different brands of Diclofenac sodium JIPBS, Vol 1 (3), 92-96.
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Safila Naveed and Fatima Qamar (2014) Simple UV spectrophotometric assay of Mefenamic acid International Journal of Pharma Sciences and Research (IJPSR), 5(7): 364-366. http://www.ijpsr.info/ijpsr-v5n7.php
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Safila Naveed and Fatima Qamar (2014) Simple UV spectrophotometric assay of Rosuvastatin, The Global Journal of Pharmaceutical Research Vol. 3 (3), pp. 1985-90,
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Safila Naveed and Amber Nawab (2014) Assay of LVFX (levofloxacin) in different formulation by UV spectroscopy IJPRDD, 1 (2), 13-16.
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Safila Naveed, Lailoona Jaweed (2014) UV spectrophotometric assay of Ketoconazole oral formulations American Journal of Biology and Life Sciences. Vol. 2, No. 5, 2014, pp. 108-111. http://www.openscienceonline.com/journal/archive?journalId=704.
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Safila Naveed, Hina Qamar, Wardha Jawaid, Urooj Bokhari. (2014) Simple UV Spectrophotometric Assay of Amlodipine. American Journal of Chemistry and Application. Vol. 1, No. 4, 2014, pp. 66-69. http://www.aascit.org/journal/archive?journalId=905.
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Safila Naveed,Farya Zafar (2014) UV Spectrophotometric Assay of Famotidine Formulations. American Journal of Pharmacy and Pharmacology. Vol. 1, No. 3, 2014, pp. 28-31. http://www.aascit.org/journal/archive? journalId=922.
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Safila Naveed, Hina Qamar, Wardha Jawaid, Urooj Bokhari (2014) Simple UV spectrophotometric assay of Glimepride Journal of Clinical Medicine Vol. 2, No. 4, 2014, pp. 94-97. http://www.openscienceonline.com/journal/archive?journalId=717.
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Safila Naveed and Fatima Qamar (2014) Simple UV spectrophotometric assay of Clarithromycin International Journal of Pharma Sciences and Research (IJPSR) Vol 5: 9: 583-585.
[22]
Safila Naveed, (2014) Analytical Method for Estimation of Losartan by using UV – Spectrophotometer Global Journal of Medical Research B.14(4):15-18.
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Safila Naveed, Lailoona Jaweed. (2014) UV Spectrophotometric Assay of Different Brands of Cephradine. Health Sciences Research. Vol. 1, No. 4, 2014, pp. 84-87. http://www.aascit.org/journal/archive?journalId=908.
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Safila Naveed, Fatima Qamar and Syeda Zainab (2014) Simple UV Spectrophotometric Assay of Bromazepam IntRJPharmSci.; 05(01); 0013-16.
[25]
Safila Naveed and Fatima Qamar (2014) A simple assay of Esomeprazole Using UV spectrophotometer The Global Journal of Pharmaceutical Research (TGJPR) 3(2); 1921-25, http://www.tgjpr.com/view-article.php?id=3433.
[26]
Safila Naveed, Shabana Naz Shah, Fatima Qamar , Nimra Waheed, and Safeena Nazeer, (2014) simple uv spectrophotometric assay of new formulation gentamycin J App Pharm Vol. 6; Issue 4: 407-410.
[27]
Safila Naveed, Shabana Naz Shah, Fatima Qamar , Nimra Waheed, and Safeena Nazeer, (2014) Simple UV spectrophotometric assay of Lincomycin, IJPRDD, 1 (2),10-12.
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Safila Naveed, Sheeba Uroog, NimraWaheed (2015) Assay of Moxifloxacin Brands Int. J. Curr. Pharm. Rev. Res., Vol. 6, Issue1, 22-27 http://ijcpr.com/ahead/.
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Safila Naveed, Zehra Ashraf and Tasleem Mukhtar (2015) Assay of Pioglitazone HCL by using UV visible spectrophotometer. British Journal of Research BJR[2][1][2015] .
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Huma Dilshad, Safila Naveed and Ghulam Sarwar (2014) Simple spectrophotometric assay of available brands of Acetaminophen tablets and their comparative study Journal of pharmacy and pharmaceutical sciences Volume 2, Issue 1, 1-4.
[31]
Safila Naveed, Fatima Qamar, Ghulam Sarwer., (2014) Percentage assay of metformin in different medium using UV- spectrophotometer BPJ0000130 - World Research Journal of Organic Chemistry Volume: 2 Issue: 1, 12-14.
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Safila Naveed, Zehra Ashraf and Tasleem Mukhtar (2014) Assay of different brands of cefadroxil by using spectrophotometric method Mintage journal of Medical and pharmaceutical Sciences Vol 3 :4;12-14.
[33]
Safila Naveed, Amber Nawab and Najaf Farooq (2014) Assay of cimitidine tablet and comparision of Local and multinational brand using UV spectrophotometer American Journal of Chemistry and Application 2014; 1(4): 70-73 Published online October 10, 2014 (http://www.aascit.org/journal/ajca).
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Safila Naveed, Fatima Qamar and Syeda Zainab (2014) Simple UV Spectrophotometric Assay Of Furosemide JIPBS, Vol 1 (3), 97-101, 2014.
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Safila Naveed and Fatima Qamar (2014) Comparative study of different Brands of Alprazolam. Global Journal of Medical Research 14 (3): 25-28. https://globaljournals.org/GJMR_Volume14/5-Comparative-Study-of-Different-Brands.pdf.
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Safila Naveed, Hina Rehman, Fatima Qamar, Syeda Zainab (2015) Method development of Perindopril using UV spectrophotometer (2015) International journal of pharmaceutical Quality Assurance: 6(1) http://ijpqa.com/#.
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Safila Naveed, Hina Rehman, Fatima Qamar, Syeda Zainab (2015) Development of a spectrophotometric method for the assay of Diclofenac potassium JIPBS, Vol 2 (1), 7-11.
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