Isolation and Characterization of 16-0-(3/, 4/, 5/– Trimethoxybenzoyl) -3-0-β-D-Diglucopyranosylcholest -15- Ene from the Leaves of Spondias mombin linn
[1]
JohnBull Onyekachi Echeme, Department of Chemistry, Michael Okpara University of Agriculture Umudike, Umuahia, Abia State, Nigeria.
[2]
Ahamefula Anslem Ahuchogu, Department of Chemistry, Michael Okpara University of Agriculture Umudike, Umuahia, Abia State, Nigeria.
[3]
Rosemary Izunwanne Uchegbu, Department of Chemistry, Alvan Ikoku Federal College of Education, Owerri, Imo State, Nigeria.
This research work was carried out to identify the bioactive constituents of the leaves of Spondias mombin linn a medicinally important plant of the Anacardiaceae family. This study revealed the presence of a steroid. Steroids have been found to be important hormone regulators which possess anti-inflammatory, antioxidant, anti-asthmatic, bronchodilator, anti-spasmodic and oxytocic properties. The chemical investigation resulted in the isolation of a new steroidal glucoside, 16-0-(3/,4/, 5/– trimethoxybenzoyl) -3-0-β-D-diglucopyranosyl cholest -15- ene. The structure was elucidated using two dimensional NMR spectroscopy, NMR ( 1H, 13C ) spectroscopy in combination with IR and MS spectra data.
Spondias Mombin, Steroidal Glucoside, Bronchodilator
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