Alumina Sulfuric Acid as a Novel Heterogeneous and Efficient Catalyst for the Synthesis of Bis (Indolyl) Methanes
[1]
Alireza Salimi Beni, Department of Chemistry, Faculty of Science, Yasouj University, Yasouj, Iran.
[2]
Maryam Zarandi, Department of Chemistry, Faculty of Science, Yasouj University, Yasouj, Iran.
[3]
Hassan Droudgarnezhad, Department of Chemistry, Faculty of Science, Yasouj University, Yasouj, Iran.
Alumina sulfuric acid as an efficient catalyst has been applied for the electrophilic substitution reaction of indoles with various aldehydes in ethanol to afford the corresponding bis(indolyl) methanes in good yields. The simplicity of this method and recyclability of catalyst are attractive features of this method. It is notable three new derivatives of bis(indolyl) methanes have been synthesized entitle{4-[Bis-(1H-indol-3-yl)-methyl]-phenyl}-diphenyl-amine, 3-[Bis-(1H-indol-3-yl)-methyl]-9-hexyl-9H-carbazole and 3-[Bis-(1H-indol-3-yl)-methyl]-9-butyl-9H-carbazole.
Aldehyde, Electrophilic Substitution, Alumina Sulfuric Acid, Indole, Ethanol, Catalyst
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