Schistosoma haematobium, a fluke worm causes urinary schistosomiasis which poses serious health hazard in tropical Africa, Asia and North America. The infection progressions require an understanding of the profile levels of some electrolytes in immune responses. Therefore, the study aims at determining the profiles level of some serum electrolytes (urea, creatinine, protein, sodium and potassium). The profile level serum electrolytes were determined using standard methods in accordance to World health organization (WHO). The results show that the electrolytes profile of infected individuals when compared with the control individuals shows that urea 1.26±0.17mg/dl, creatinine 1.33±0.05mg/dl, protein 53±2.25mg/dl, sodium 129±2.25mg/dl, Potassium 4.20±0.2md/dl and urea 2.4±0.42mg/dl, creatinine 1.2±0.44mg/dl, protein 66±1.41mg/dl, sodium 135±1.41mg/dl, potassium 4.10±0.19mg/dl respectively. Proteinuria profile level was statistically significant (x²=13.40, p<0.05), when infected was compared with non-infected. The infected individuals had higher mean concentration of serum urea (4.49±0.88Mmol/l) and these differences were statistically significant at P<0.05 when compared with the control (3.86±0.32Mmol/l). The mean concentration of serum creatinine (110.76±10.40Mmol/l) and protein in urine (22.46±3.01Mmol/l) in the infected volunteers were significantly at P<0.05 when compared with the control volunteers (101.66±4.77Mmol/l and 13.66±1.42Mmol/l) respectively. The relationship between Schistosoma parasitaemia, serum creatinine and protein in urine were positively correlated with r=0.61 and r=0.47 respectively. The serum profile level of urea was negatively correlated with Schistosoma parasitaemia. The profile levels of serum electrolytes and intensity of infection of infected and control individuals showed no significant difference (P=0.05). To this end, this researched data deduce that these electrolytes are major immunological indicators in the immunopathology of S. haematobium infection. Furthermore, it is proposed that raised profile levels of these electrolytes should aid as a bio - marker of schistosomes diagnosis in positive individuals in our locality.

Immunopathology, Serum, Electrolytes, Schistosoma haematobium, Individuals, Parasitaemia