Prevalence and Antimicrobial Susceptibility of Urinary Pathogens among Pregnant Women in the Lagos University Teaching Hospital
[1]
Ezeamaramu F. U., Department of Medical Microbiology & Parasitology, College of Medicine, University of Lagos, Lagos, Nigeria.
[2]
Omonigbehin E. A., Department of Biological Science, College of Science and Technology Covenant University, Ota, Ogun State Nigeria.
[3]
Obi I. A., Department of Medical Microbiology & Parasitology, College of Medicine, University of Lagos, Lagos, Nigeria.
[4]
Fowora M. A., Molecular Biology/Biotechnology Division, Nigerian Institute of Medical Research, Lagos, Nigeria.
[5]
Awoderu O. B., Microbiology Division, Nigerian Institute of Medical Research, Lagos, Nigeria.
[6]
Olamijulo J. A., Department of Obstetrics and Gynaecology, College of Medicine University of Lagos, Lagos, Nigeria.
[7]
Ekpokpobe P. E., Department of Chemistry Education, Federal College of Education Technical, Lagos, Nigeria.
[8]
Coker A. O., Department of Medical Microbiology & Parasitology, College of Medicine, University of Lagos, Lagos, Nigeria.
This study was carried out to determine the prevalence, antimicrobial susceptibility pattern Beta Lactamase and Extended Beta Lactamase Production (ESBL) of urinary pathogens among pregnant women in Lagos University Teaching Hospital. One hundred and forty five urine specimens were cultured, antimicrobial drug susceptibility was carried out using Kirby-Bauer technique, the multiple drug resistance isolates were tested for beta lactamase and ESBL production using starch paper and double synergy techniques respectively. Two hundred and thirty three urinary pathogens were isolated, 32.1% Gram positives and 67.0% negatives. High resistant were observed in amoxicillin, ceftazidime and augmentin with 100%, 96% and 94.9% respectively. The prevalence of multiple drug resistance isolates observed was (91.8%) of which ESBL producers were (25.0%). This study shows that most of the pregnant women harbor one or more urinary pathogens that are antibiotic resistant. Thus, suggest a continuous awareness of the risk involved in Urinary tract infection in pregnancy.
Double Synergy, ESBL, Resistance, Starch Paper, Susceptibility
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