UV Spectrophotometric Assay of Ketoconazole Oral Formulations
[1]
Safila Naveed, Faculty of Pharmacy, Jinnah University for women, Karachi.
[2]
Lailoona Jaweed, Faculty of Pharmacy, Jinnah University for women, Karachi.
Ketoconazole is an antifungal drug use for the treatment of many systemic and external antifungal agents. It is used for the different types of fungi species. It may cause different side effects specifically in males it causes decrease in testosterone concentration so it should be use with caution in males. It is also used in many external fungal infection seborrheic dermatitis. The assay was done by using 3 available brands of ketoconazole in market, different dilution of 100ppm, 50ppm and 25ppm were made and analyzed, percent assay was determine by measuring absorbance. Furthermore absorbance at different concentration was determine and on applying regression it is concluded that there is a linear relationship between concentration and absorption.
Ketoconazole, Spectrophotometer, Oral Formulation
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