Comparative Study of the Effects of the Use of Combined Oral Pills and Progestin-Only Pills in Nigerian Females
This study involved fifty apparently healthy females on oral contraceptives (test) and another fifty apparently healthy females not on oral contraceptives (control). Both groups were aged 16-40 years of age. The test group have been on oral contraceptive for at least 5 months. Test group was grouped into progestin-only pill (POP) users and combined oral pill (COP) users. The following parameters were analyzed, packed cell volume (PCV), erythrocyte sedimentation rate (ESR), Haemoglobin Estimation (Hb), Red cell indices, total white blood count (TWBC) and platelet count using standard manual methods. The results showed significant increase (P<0.05) in platelet counts, ESR and TWBC when compared with control. Significant difference (p<0.05) was also seen in platelet count and WBC when progestin-only pill (POP) users were compared with combined oral pill (COP) users. These findings suggest that oral contraceptive (OC) users could be predisposed to thrombosis with COP users having greater risk than POP users.
Oral Contraceptives, Thrombosis, Nigerian Females
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