Serum Lipid Profiles in Chronic Kidney Disease Patients on Haemodialysis at Parkview Renal Unit
[1]
Sibusisiwe Sibanda, Department of Medical Laboratory Sciences, University of Zimbabwe, Harare, Zimbabwe.
[2]
Danai Tavonga Zhou, Department of Medical Laboratory Sciences, University of Zimbabwe, Harare, Zimbabwe.
Chronic kidney disease is a condition where there is loss of kidney function over time. Sometimes acute kidney injury develops into chronic kidney disease. In such situations, renal replacement therapy may be prescribed which includes kidney transplant, peritoneal dialysis, hemodialysis and hemodiafiltration. Haemodialysis is a process that uses diffusion principles to remove metabolites from the blood using a dialyzer. Chronic kidney disease patients are known to be at risk for cardiovascular diseases and the lipid profile and cardiovascular indices may be used to assess this. This cross-sectional study was used to assess lipid dysfunction in 55 chronic kidney disease patients, on haemodialysis, attending Parkview Renal Unit in Harare, Zimbabwe. Total cholesterol (TC) levels of all patients were in the normal ranges as recommended by the National Cholesterol Education Program (NCEP) and The Kidney Dialysis Outcome Quality Initiative. Approximately 82% of the population had decreased high density lipoprotein (HDLc), 7% had elevated low density lipoprotein (LDLc), and 2% had a high LDLc/HDLc ratio while 4% had a high TC/HDLc ratio. Of the chronic kidney disease patients on haemodialysis at Parkview Renal Unit, at most 82% are at a risk of developing cardiovascular disease when determined using reduced HDLc levels as an index but risk is low when using CVD indeces.
Chronic Kidney Disease, Haemodialysis, Lipid Profile, HDLc, LDLc, TC
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