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Current Management Progress and Future Direction of Schistosomiasis: A Review
Current Issue
Volume 5, 2017
Issue 5 (October)
Pages: 39-46   |   Vol. 5, No. 5, October 2017   |   Follow on         
Paper in PDF Downloads: 18   Since Aug. 14, 2017 Views: 619   Since Aug. 14, 2017
C. M. A. Gause Miraj, School of Pharmaceutical Science, Jiangnan University, Wuxi, China.
Wen-Hua Fan, School of Pharmaceutical Science, Jiangnan University, Wuxi, China.
Bainian Feng, School of Pharmaceutical Science, Jiangnan University, Wuxi, China.
Schistosomiasis, also known as snail fever; is a tropical diseases due to the parasite Schistosoma trematode worms. It comes second only to malaria as its impact on the society. Around 230 million people are at highly risk in the world. Combines with others such as diarrhea, chronic pain, anaemia, undernutrition, the disease is also a major risk factor for HIV infection in which caused by female urogenital schistosomiasis. The shistosomiasis parasites modulate the immune response of the host once the egg deposition has started. Until now, the most effective antischistosome drug is praziquantel (PZQ). In this review, we discuss some aspects about new antischistosome drug as well as vaccine development.
Schistosoma, Oxadiazole-2-oxide Analogues, Antischistosomal Activity, Neglected Tropical Disease
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