Iron Profile Studies of a Group of Healthy University Students
[1]
Anslem O. Ajugwo , Department of Haematology and Blood Transfusion, Madonna University, Elele, Nigeria.
[2]
Damian C. Ukaji , Department of Haematology and Blood Transfusion, Madonna University, Elele, Nigeria.
[3]
Christine O. Adinuba , Department of Public Health and Policy, Morgan State University, Baltimore, USA.
[4]
Ikechukwu R. Nnadozie , Department of Microbiology/Haematology, Imo State University Teaching Hospital, Orlu, Nigeria.
[5]
Obialor E. Onukogu , Department of Accident & Emergency, Imo State University Teaching Hospital, Orlu, Nigeria.
[6]
Francesca C. Uzoma-Esemonu , Department of Microbiology/Haematology, Imo State University Teaching Hospital, Orlu, Nigeria.
Iron is a very important element required for haemopoietic activity hence the need to assess iron profile of some apparently healthy university students. Twenty-five (25) male and twenty-five (25) female students of Madonna University, Elele, were used for this study. The subjects gave their consent and 5ml of venous blood sample was collected. The samples were analyzed using standard methods. Parameters analyzed include Total serum Iron (TSI), Unsaturated Iron Binding Capacity (UIBC), Total Iron Binding Capacity (TIBC), Haemoglobin concentration (Hb) and Packed Cell Volume (PCV). The result obtained showed that the males had a significantly (p<0.05) higher values of 43.77±3.5% and15.20±1.1g/dl than females with 39.83±3.1% and 13.52±1.1g/dl for PCV and Hb respectively. Result for the Total Serum Iron gave a value of 17.26±2.4 µmol/l for males and 13.40±2.7 µmol/l for females. Conversely, UIBC and TIBC were significantly (p<0.05) lower in males with 45.95±5.2 and 63.21±4.4 µmol/l than in females with values of 60.14±6.8 and 73.55±60 µmol/l respectively. From the results of the study, the males had a higher iron content than the females while the females have higher demand for iron.
Iron, Haemoglobin, Packed Cell Volume, Haemopoietic Activity, Iron Binding Capacity
[1]
Kleinman, R.E. (1998). Pediatric Nutrition Handbook. 4th ed. Elk Grove Village, Ill: American Academy of Pediatrics.
[2]
Andrews, C.A (1999). Disorder of Iron metabolism, The New England Journal of Medicine.
[3]
Thorup, O.A. (1987). Disorders of iron metabolism: In Fundamentals of Clinical Hematology, WB Sanders, Philadelphia p 212 – 243.
[4]
Lewis, S. M., Bain, B. J. and Bates, I. (2006). Iron metabolism: In Practical Haematology. 10th Edition. Elsevier Publishers, New Delhi. p132 – 135.
[5]
Food and Agriculture Organization of the United Nations, Requirements of vitamin
[6]
A, iron, folate and vitamin B,2. (2005) Report of a Joint FAO/WHO Expert Group. Rome, FAO. National Institute of Nutrition (1972). Annual Report of Indian Council of Medical Research. Hyderabad, India, p. 18.
[7]
Zhang, A. S., Xiong, S., Tsukamoto, H. (2004) Localization of iron metabolism-related mRNAs in rat liver indicate that HFE is expressed predominantly in hepatocytes. Blood 103: 1509–1514.
[8]
Hamill, R.L., Woods, J.C., Cook, B.A. (1991). Congenital atransferrinemia: a case report and review of the literature. Am. J. Clin. Pathol., 96:215-8.
[9]
Hayashi, A., Wada, Y., Suzuki, T., Shimizu, A. (1993) Studies on familial hypotransferrinemia: unique clinical course and molecular pathology. Am. J Hum Genet. 53:201-13.
[10]
Chen, E.C., Danis, P.G. and Tweed, E. (2009). Clinical inquiries. Menstrual disturbances in perimenopausal women: what's best? Journal of Family Practice; 58 (6): 3-8.
[11]
Cheesbrough M (1998). District Laboratory Practice in Tropical Countries. Part 1. Cambridge University Press UK. Pp318
[12]
Lewis, S. M., Bain, B. J. and Bates I. (2006). Iron deficiency anaemia and iron overload. In: Dacie and Lewis Practical Haematology. 10th Ed. Elsevier New Delhi. 141 – 45.
[13]
Beaumont, H., Augood, C., Duckitt, K. and Lethaby, A. (2007). Danazol for heavy menstrual bleeding. Cochrane Database System Review; 45 (3): 10-17.
[14]
Dietrich, J.E. (2007). Von Willebrand's disease. Journal of Pediatrics, Adolescence and Gynecology; 20 (3): 153-155.
[15]
Harlow, S.D. and Ephross, S.A. (1995). Epidemiology of menstruation and its relevance to women's health. Epidemiology Review. 17 (2): 265-286.
