Effect of Murraya Koenigii, Catharanthus Roseus and Psidium Guajava Leaves Extract on Blood Glucose in Alloxan Induced Diabetic Rats
[1]
Saghir Ahmad Jafri, Prof.of Physiology & Chief Coordinator, FMH College of Medicine and Dentistry, Shadman, Lahore, Pakistan.
[2]
Khaleeq ur Rehman, Prof. of Urology, FMH College of Medicine and Dentistry, Shadman, Lahore, Pakistan.
[3]
M. Qasim, AP, Biotech.Dept, GC Univ. Faisalabad, Pakistan.
[4]
Kalsoom , AP, Biochemistry, the University of Lahore, Pakistan.
The present work was carried out to observe the hypoglycemic activity of Murraya koenigii, Catharanthus and psidium guajava leaves extract in alloxan induced diabetic rats.For this purpose 50 rats were divided into five groups of 10 rats each. The group 1 was control and given normal feed. The group 2 was made diabetic (by alloxan) injection and given normal feed. Group 3 was diabetic given normal feed and treated with Murraya koenigii leaves extract. Group 4 was also diabetic, given normal feed and treated with Catharanthus roseus leaves extract. Group 5 was diabetic, given normal feed and treated with Psidium guajava leaves extract. All the rats were given herbal extracts 200 mg//kg body weight/ day for 42 days. It was observed that Murraya koenigii and Catharanthus roseus decreased blood sugar level more than Psidium guajava. The results were subjected to statistical analysis using SPSS (ANOVA & Mean ± SE) according to (1), and revealed that Murraya koenigii, Catharanthus roseus and Psidium guajava leaves extract have blood sugar lowering effect significantly higher(P<0.05) in diabetic rats than normal ones who were not given herbal extract.
Diabetes, Murraya Koenigii, Catharanthus, Psidium Guajava, Alloxan
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